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61367-17-7

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61367-17-7 Usage

Description

cis-Ethyl 4-aMinocyclohexanecarboxylate hydrochloride, also known as Ethyl cis-4-Aminocyclohexanecarboxylate Hydrochloride, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique chemical structure, which allows it to participate in multiple chemical reactions and form a wide range of products.

Uses

Used in Pharmaceutical Industry:
cis-Ethyl 4-aMinocyclohexanecarboxylate hydrochloride is used as a reagent for the synthesis of arylpiperazinylalkyl and arylpiperazinylalkylthio quinazolinones. These compounds act as dual 5-HT1a agonists and 5-HT3 antagonists, which are essential in the treatment of irritable bowel syndrome (IBS). The unique properties of this hydrochloride salt enable the development of effective medications that can alleviate the symptoms of IBS and improve the quality of life for patients suffering from this condition.

Check Digit Verification of cas no

The CAS Registry Mumber 61367-17-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,3,6 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 61367-17:
(7*6)+(6*1)+(5*3)+(4*6)+(3*7)+(2*1)+(1*7)=117
117 % 10 = 7
So 61367-17-7 is a valid CAS Registry Number.

61367-17-7Downstream Products

61367-17-7Relevant articles and documents

COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 POLYPEPTIDES

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Paragraph 1472-1473, (2019/06/07)

The present disclosure relates to bifunctional compounds, which find utility as modulators of Interleukin-1 Receptor-Associated Kinase 4 (IRAK-4); the target protein). In particular, the present disclosure is directed to bifunctional compounds, which contain on one end a Von Hppel-Lindau, cereblon, ligand which binds to the E3 ubiquitin ligase and on the other end a moiety which binds the target protein, such that the target protein is placed in proximity to the ubiquitin ligase to effect degradation (and inhibition) of target protein. The present disclosure exhibits a broad range of pharmacological activities associated with degradation/inhibition of target protein. Diseases or disorders that result from aggregation or accumulation of the target protein are treated or prevented with compounds and compositions of the present disclosure.

METHOD FOR PRODUCING DICARBOXYLIC ACID COMPOUND

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Paragraph 0203-0205, (2018/06/09)

It is an object of the present invention to provide an excellent method for producing an excellent therapeutic agent. The solution of the present invention is as shown in the following scheme: wherein R1 represents a C1-C6 alkyl group, R2 represents a C1-C6 alkyl group, and R3 represents a C1-C6 alkyl group.

PYRIDIN-2(1H)-ONE DERIVATIVES AS JAK INHIBITORS

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Page/Page column 76, (2013/03/26)

New pyridin-2(1H)-one derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

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