61389-11-5Relevant academic research and scientific papers
Small-Molecule Choline Kinase Inhibitors as Anti-Cancer Therapeutics
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Page/Page column 25; 27-28, (2011/10/31)
Small molecule choline kinase inhibitors having the following formula: are provided herein. Also provided herein are pharmaceutical compositions containing Formula I compounds, together with methods of treating cancer, methods of inhibiting choline kinase enzymatic activity, and methods of treating tumors by administering an effective amount of a Formula I compound.
Robust multidentate ligands for diagnosis and anti-viral drugs for influenza and related viruses
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Page/Page column 5; sheet 6, (2008/12/07)
Design and synthesis of a novel library of compounds comprising a spacer with an attachment element on one terminus and a recognition element on the other terminus is presented. The library of compounds can be attached to a solid support and used as an in
Synthesis of soluble multivalent glycoconjugates that target the Hc region of botulinum neurotoxin A
Kale, Ramesh R.,Clancy, Colin M.,Vermillion, Rebecca M.,Johnson, Eric A.,Iyer, Suri S.
, p. 2459 - 2464 (2008/02/13)
The design, synthesis, and initial inhibitory studies of di- and tetravalent glycoconjugates that target the heavy chain of botulinum neurotoxin A are reported.
Arylamide dendrimers with flexible linkers via haloacyl halide method
Vinogradov, Sergei A.
, p. 1761 - 1764 (2007/10/03)
(Chemical Equation Presented) Soluble arylamide dendrons with flexible linkers, peripheral ester or carboxyl groups (R), and focal amino or halogen functionalities (F) were synthesized from aryl glycineamide (AG) building blocks. The AG blocks were prepar
