61418-15-3

Upstream product

• 104206-29-3 methyl α-<2-hydroxy-3-methoxy-5-oxo-4-(3,4,5-trimethoxyphenyl)-2,5-dihydrofuran-2-yl>-4-methoxyphenylacetate 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 61418-12-0 3-methoxy-4-(3,4,5-trimethoxyphenyl)maleic anhydride 
• 32766-61-3 4-methoxyphenylglyoxylate methyl ester 
• 137531-75-0 5-dimethoxyphosphoryl-4-methoxy-3-(3,4,5-trimethoxyphenyl)furan-2(5H)-one 
• 61418-13-1 4-methoxy-3-(3,4,5-trimethoxy-phenyl)-5H-furan-2-one 

Downstream Products

• 25328-77-2 E-gomphidic acid 
• 104206-34-0 methyl (E)-α-<3-methoxy-5-oxo-4-(3,4,5-trimethoxyphenyl)-2,5-dihydrofuran-2-ylidene>(4-methoxyphenyl)acetone 

Relevant academic research and scientific papers

Maleic Anhydrides in Synthesis. Preparation of Furan-2(5H)-one Phosphonate Derivatives and a New Synthesis of Pulvinic Acids and Pulvinone Analogues

Reactions between substituted maleic anhydrides, viz. 1, and sodium dimethyl phosphite in refluxing benzene are shown to lead to the corresponding furan-2(5H)-one phosphonates 2 and 8.Wadsworth-Emmons olefination reactions involving 2 and heteroarylaldehy

New Syntheses of Pulvinic Acids via Reformatsky-type Reactions with Aryl methoxymaleic Anhydrides

The reaction of zinc enolates, viz (13), derived from arylacetates with 2-aryl-3-methoxymaleic anhydrides gives β-hydroxy ester intermediates viz(17) which can be dehydrated to Z- and E-isomers of permethylated pulvinic acids.Thus, the intermediate (17) d

A NEW SYNTHESIS OF PULVINIC ACIDS.

Reaction of zinc enolates e.g. (6) derived from arylacetates with 2-aryl-3-methoxymaleic anhydrides e.g. (3) gives intermediates viz (8) which can be dehydrated to Z-and E-isomers of permethylated pulvinic acids; treatment of the latter with trimethylsily