32766-61-3

Basic information

• Product Name: Methyl 2-(4-methoxyphenyl)-2-oxoacetate
• Synonyms: Methyl 2-(4-methoxyphenyl)-2-oxoacetate;4-Methoxy-oxo-benzeneacetic acid methyl ester
• CAS NO: 32766-61-3
• Molecular Formula: C₁₀H₁₀O₄
• Molecular Weight: 194.184
• Mol File: 32766-61-3.mol
• Article Data: 62

Chemical Properties

• Melting Point: 54 °C
• Boiling Point: 303.2±25.0 °C(Predicted)
• Appearance: /
• Density: 1.177±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Methyl 2-(4-methoxyphenyl)-2-oxoacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 2-(4-methoxyphenyl)-2-oxoacetate(32766-61-3)
• EPA Substance Registry System: Methyl 2-(4-methoxyphenyl)-2-oxoacetate(32766-61-3)

Safety Data

• Hazardous Substances Data: 32766-61-3(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 7099-91-4 p-methoxybenzoylformic acid 
• 23786-14-3 4-methoxy-phenyl acetic acid methyl ester 
• 6889-78-7 4'-(methoxy)-3-hydroxyflavone 
• 17640-25-4 methyl 2,2-dichloro-2-methoxyacetate 
• 100-66-3 methoxybenzene 
• 64-19-7 acetic acid 
• 18166-02-4 N-trimethylsilylmethylamine 
• 124-38-9 carbon dioxide 
• 75748-09-3 (4-methoxybenzoyl)trimethylsilane 
• 100-07-2 4-methoxy-benzoyl chloride 
• 74-88-4 methyl iodide 
• 123-11-5 4-methoxy-benzaldehyde 
• 66985-48-6 2-(4-methoxyphenyl)-2-(trimethylsilyloxy)acetonitrile 

Downstream Products

• 156-38-7 4-hydroxyphenylacetate 
• 33131-26-9 2-(4-Methoxy-phenyl)-3-methyl-but-2-enoic acid methyl ester 
• 137531-85-2 (Z)-O-methylisopinastric acid 
• 22628-24-6 (E)-4-methoxy-5-(α-methoxycarbonyl-4-methoxybenzylidene)-3-phenylfuran-2(5H)-one 
• 104206-34-0 methyl (E)-α-<3-methoxy-5-oxo-4-(3,4,5-trimethoxyphenyl)-2,5-dihydrofuran-2-ylidene>(4-methoxyphenyl)acetone 
• 61418-15-3 methyl (Z)-α-<3-methoxy-5-oxo-4-(3,4,5-trimethoxyphenyl)-2,5-dihydrofuran-2-ylidene>(4-methoxyphenyl)acetone 
• 104383-29-1 methyl (S)-α-hydroxy-(4-methoxyphenyl)acetate 
• 32174-38-2 methyl (R)-2-hydroxy-2-(4-methoxyphenyl)acetate 
• 81316-44-1 trans-2,3-bis(carbomethoxy)-p,p'-dimethoxystilbene oxide 
• 81316-37-2 cis-2,3-bis(carbomethoxy)-p,p'-dimethoxystilbene oxide 
• 13305-14-1 methyl 2-hydroxy-2-(4-methoxyphenyl)acetate 
• 850794-55-7 methyl 2-(4-methoxyphenyl)-2,3-epoxypropanoate 
• 1224978-74-8 (R)-methyl 2-cyano-2-(4-methoxyphenyl)-2-trimethylsiloxyacetate 
• 1408233-50-0 N,N-dihexyl-2-(4-methoxylphenyl)glycine methyl ester 

Relevant articles and documents

Unraveling two pathways for NHPI-mediated electrocatalytic oxidation reaction

Two pathways for N-hydroxyphthalimide (NHPI)-mediated electrocatalytic oxidation using phenylacetate derivatives as template substrates were first reported for benzylic C[sbnd]H oxidation to oxygenated and non-oxygenated products. DFT calculation indicates that the hydrogen-atom transfer (HAT) process between phthalimido-N-oxyl (PINO) and substrate is a rate-determined step. Aromatic α-keto esters and 2-((1,3-dioxoisoindolin-2-yl)oxy)-2-aryl acetate obtained by cross-coupling between benzylic radical and PINO can be selectively synthesized through controlling the concentration of PINO radical. This method provides a deep understanding for selective weak C[sbnd]H oxidation using NHPI as redox mediator.

Methyl Benzoylformate Derivative Norrish Type I Photoinitiators for Deep-Layer Photocuring under Near-UV or Visible LED

We designed and prepared a series of methyl benzoylformate (MBF) derivatives Norrish type I photoinitiators (MBFs) for light-emitting diode (LED)-induced photopolymerization through computer simulation. The potential photolysis mechanism of MBFs under LED at 405 nm was explored by steady-state photolysis, nuclear magnetic resonance, and electron spin resonance. The as-synthesized photoinitiator dimethyl 1,4-dibenzoylformate (DM-BD-F) can efficiently initiate free radical photopolymerization of acrylate monomers under LED irradiation at 405 nm. Moreover, we predicted well the photoinitiating capability of MBFs through the cleavage exothermy (ΔH) calculated by triplet bond dissociation energy (BDE) and triplet energy (ET). Significantly, based on the weak absorption of MBFs at 405 nm, MBFs were successfully applied to deep-layer photocuring and the curing depth reached 6.5 cm after the irradiation of LED at 405 nm for 30 s. This research provides a new idea and efficient strategy for the molecular design of photoinitiators for deep-layer photocuring.

Photoinduced Diverse Reactivity of Diazo Compounds with Nitrosoarenes

A diverse reactivity of diazo compounds with nitrosoarene in an oxygen-transfer process and a formal [2 + 2] cycloaddition is reported. Nitosoarene has been exploited as a mild oxygen source to oxidize an in situ generated carbene intermediate under visible-light irradiation. UV-light-mediated in situ generated ketenes react with nitosoarenes to deliver oxazetidine derivatives. These operationally simple processes exemplify a transition-metal-free and catalyst-free protocol to give structurally diverse α-ketoesters or oxazetidines.