61440-87-7

Upstream product

• 60598-10-9 2,3-Bis-(2,4-dimethyl-phenyl)-cycloprop-2-enone 
• 4214-28-2 1-iodo-2,4-dimethylbenzene 
• 471-25-0 Propiolic acid 
• 16017-30-4 1-ethynyl-2,4-dimethylbenzene 
• 108-38-3 m-xylene 

Downstream Products

• 1564265-54-8 ethyl 4,5-bis(2,4-dimethylphenyl)-3-oxo-2-phenylcyclopenta-1,4-dienecarboxylate 
• 1564265-55-9 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(4-fluorophenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-56-0 ethyl 2-(4-chlorophenyl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-57-1 ethyl 2-(4-bromophenyl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-58-2 ethyl 4,5-bis(2,4-dimethylphenyl)-3-oxo-2-(4-(trifluoromethyl)phenyl)cyclopenta-1,4-dienecarboxylate 
• 1564265-59-3 ethyl 2-(4-cyanophenyl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-60-6 ethyl 2-(2,4-dichlorophenyl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-di-enecarboxylate 
• 1564265-61-7 ethyl 2-(4-acetylphenyl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-diene-carboxylate 
• 1564265-62-8 methyl 4-(3,4-bis(2,4-dimethylphenyl)-2-(ethoxycarbonyl)-5-oxocyclopenta-1,3-dien-1-yl)benzoate 
• 1564265-63-9 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(4-ethylphenyl)-3-oxocyclopenta-1,4-dienecarboxylate 
• 1564265-64-0 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(4-methoxyphenyl)-3-oxocyclopenta-1,4-di-enecarboxylate 
• 1564265-65-1 ethyl 2-([1,1'-biphenyl]-4-yl)-4,5-bis(2,4-dimethylphenyl)-3-oxocyclopenta-1,4-di-enecarboxylate 
• 1564265-66-2 ethyl 4,5-bis(2,4-dimethylphenyl)-3-oxo-2-m-tolylcyclopenta-1,4-dienecarboxylate 
• 1564265-67-3 ethyl 4,5-bis(2,4-dimethylphenyl)-2-(naphthalen-2-yl)-3-oxocyclopenta-1,4-diene-carboxylate 

Relevant academic research and scientific papers

A convenient regioselective synthesis of cyclopentadienones via palladium-catalyzed [2+2+1] cyclocarbonylation of alkynes

A simple and efficient synthesis of cyclopentadienones via palladium-catalyzed cyclocarbonylation of alkynes under atmospheric pressure of carbon monoxide has been developed. The transformation was carried out under mild and ligand-free conditions, a wide range of substrates and exceptional functional group tolerance.

One-pot synthesis of 1,4-diarylsubstituted 1,3-diynes from the sequential coupling reactions of aryl iodides and propiolic acid

1,4-Disubstituted 1,3-dialkynes were obtained from the one-pot palladium/copper-catalyzed coupling reactions of aryl iodide and propiolic acid. The optimized catalytic system consisted of 5.0 mol % Pd(PPh3) 2Cl2, 10 mol % dppb, 10 mol % CuI, 2.4 equiv of DBU, and 1.2 equiv of K2CO3. The coupling reaction was carried out at 30 °C for 6 h and subsequently at 80 °C for 3 h.