61447-86-7Relevant academic research and scientific papers
SUBSTITUTED DIAMINOPYRIMIDYL COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH
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Paragraph 0423; 0441, (2015/07/02)
Provided herein are diaminopyrimidyl Compounds having the following structures: wherein X, L, R1, and R2 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidyl Compound, and methods for treating or preventing PKC-theta-mediated disorders, or a condition treatable or preventable by inhibition of a kinase, for example, PKC-theta.
An NMR tool for cyclodextrin selection in enantiomeric resolution by high-performance liquid chromatography
Laverde Jr., Antonio,Da Conceicao, Gelson J. A.,Queiroz, Sonia C. N.,Fujiwara, Fred Y.,Marsaioli, Anita J.
, p. 433 - 442 (2007/10/03)
Complexation-induced chemical shifts and diffusion coefficients (HR-DOSY) of enantiomers with native and derivatized cyclodextrins were used for calculations of the apparent binding constants of three cyclohexanone inclusion complexes. Correlations between these data and high-performance liquid chromatography were established, revealing that this approach can be applied as an alternative method to predict enantiomeric discrimination. Copyright
