614750-85-5

Basic information

• Product Name: Phosphonic acid, P-[(6-Methyl-2-pyridinyl)(phenylaMino)Methyl]-, diphenyl ester
• Synonyms: Phosphonic acid, P-[(6-Methyl-2-pyridinyl)(phenylaMino)Methyl]-, diphenyl ester;diphenyl((6-methylpyridin-2-yl)(phenylamino)methyl)phosphonate
• CAS NO: 614750-85-5
• Molecular Formula: C₂₅H₂₃N₂O₃P
• Molecular Weight: 430.435481
• Mol File: 614750-85-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Phosphonic acid, P-[(6-Methyl-2-pyridinyl)(phenylaMino)Methyl]-, diphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, P-[(6-Methyl-2-pyridinyl)(phenylaMino)Methyl]-, diphenyl ester(614750-85-5)
• EPA Substance Registry System: Phosphonic acid, P-[(6-Methyl-2-pyridinyl)(phenylaMino)Methyl]-, diphenyl ester(614750-85-5)

Safety Data

• Hazardous Substances Data: 614750-85-5(Hazardous Substances Data)

Usage

General Description

Phosphonic acid, P-[(6-Methyl-2-pyridinyl)(phenylamino)methyl]-, diphenyl ester is a chemical compound with the molecular formula C24H22N2O3P. It is used as an intermediate for various organic synthesis and pharmaceutical applications, where it acts as a catalyst or reagent. Phosphonic acid, P-[(6-Methyl-2-pyridinyl)(phenylaMino)Methyl]-, diphenyl ester is also known for its potential use in the development of new materials, such as polymers and nanomaterials, due to its unique chemical properties. Additionally, it has been studied for its potential biological activities, such as antimicrobial and antiviral properties. However, caution should be exercised when handling this compound due to its potential hazards and reactivity with other chemicals. Overall, the compound has a wide range of potential industrial and research applications due to its versatile chemical properties.

Upstream product

• 1122-72-1 6-methyl-2-pyridinecarboxaldehyde 
• 4712-55-4 diphenyl hydrogen phosphite 
• 41839-47-8 diphenoxyphosphine 
• 62-53-3 aniline 

Downstream Products

• 476472-02-3 1-(6-methylpyridin-2-yl)-2-(quinolin-4-yl)ethan-1-one 
• 813449-09-1 2-[3-hydroxy-4-nitrophenyl]-1-[6-methylpyridin-2-yl]-ethanone 
• 614750-82-2 1-(6-methylpyridin-2-yl)-2-[1,2,4]triazolo-[1,5-a]pyridin-6-yl-ethanone 
• 356560-84-4 1-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-2-(6-methylpyridin-2-yl)ethane-1,2-dione 
• 1352609-09-6 N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-3-vinylaniline 
• 1352609-64-3 3-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)-4-((dimethylamino)methyl)benzonitrile 
• 1352609-77-8 N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-2-fluoro-N-methylaniline 
• 1352610-23-1 3-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)benzonitrile 
• 1352610-24-2 3-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)benzamide 
• 1352609-89-2 6-(2-(dimethoxymethyl)-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridine 
• 1352609-91-6 4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazole-2-carbaldehyde 
• 1352610-22-0 N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methyl)-3-vinylaniline sulfate 
• 607737-87-1 4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoline 

Relevant articles and documents

SUBSTITUTED 1,5-NAPHTHYRIDINES OR QUINOLINES AS ALK5 INHIBITORS

The present disclosure provides inhibitors of activin receptor-like kinase 5 (ALK5). Also disclosed are methods to modulate the activity of ALK5 and methods of treatment of disorders mediated by ALK5.

4- (HETEROCYCLYL- FUSED PHENYL)- 3- (PHENYL OR PYRID -2- YL) PYRAZOLES AS INHIBITORS OF THE ALK-5- RECEPTOR

The invention relates to novel pyrazole derivatives which are inhibitors of the transforming growth factor, ("TGF")-β signalling pathway, in particular, the phosphorylation of smad2 or smad3 by the TGF-β type I or activin-like kinase ("ALK")-5 receptor, m