614754-30-2

Basic information

• Product Name: 2-Piperidinone,3-hydroxy-1-methyl-,(3R)-(9CI)
• Synonyms: 2-Piperidinone,3-hydroxy-1-methyl-,(3R)-(9CI)
• CAS NO: 614754-30-2
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.16
• Product Categories: AMINETERTIARY
• Mol File: 614754-30-2.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Piperidinone,3-hydroxy-1-methyl-,(3R)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Piperidinone,3-hydroxy-1-methyl-,(3R)-(9CI)(614754-30-2)
• EPA Substance Registry System: 2-Piperidinone,3-hydroxy-1-methyl-,(3R)-(9CI)(614754-30-2)

Safety Data

• Hazardous Substances Data: 614754-30-2(Hazardous Substances Data)

Upstream product

• 614754-05-1 N-methyl-2,5-dibromovaleramide 
• 614754-19-7 3-acetoxy-1-methyl-2-piperidinone 
• 19365-01-6 1-methyl-3-hydroxy-2(1H)-pyridinone 
• 49785-85-5 (R,S)-N-methyl-3-bromo-2-piperidone 
• 89180-84-7 2,5-Dibromopentanoic Acid Bromide 
• 94475-65-7 3-(benzyloxy)-1-methylpyridin-2(1H)-one 
• 94475-64-6 3-benzyloxy-2-hydroxypyridine 
• 16867-04-2 dihydroxypyridine 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF NF-kB INDUCING KINASE

The present invention relates to compounds that inhibit NIK and pharmaceutical compositions comprising such compounds and methods of using the same. These compounds and pharmaceutical compositions are envisaged to be useful for preventing or treating diseases such as cancer (such as B-cell malignancies including leukemias, lymphomas and myeloma), inflammatory disorders, autoimmune disorders, immunodermatologic disorders such as palmoplantar pustulosis and hidradenitis suppurativa, and metabolic disorders such as obesity and diabetes.

Chemoenzymatic enantioselective synthesis of 3-hydroxy-2-pyrrolidinones and 3-hydroxy-2-piperidinones

The enantioselective synthesis of 3-hydroxypyrrolidin-2-ones and 3-hydroxy piperidin-2-ones has been carried out in high enantiomeric excess employing immobilized lipase from Pseudomonas cepacia.