6149-45-7 Usage
General Description
3-Hydroxy-3-methylbutanoic acid methyl ester, also known as HMB, is a chemical compound often used as a nutritional supplement and is known to have potential anti-catabolic and anabolic effects. HMB is a metabolite of the amino acid leucine and has been shown to promote muscle protein synthesis and reduce muscle protein breakdown, making it popular among athletes and bodybuilders for muscle building and recovery. In addition to its effects on muscle, HMB has also been studied for its potential impact on various health conditions, including muscle wasting, osteoporosis, and cancer cachexia. Overall, HMB shows promise as a nutritional supplement for enhancing muscle mass and strength, and potentially for managing certain health conditions associated with muscle breakdown.
Check Digit Verification of cas no
The CAS Registry Mumber 6149-45-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,4 and 9 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 6149-45:
(6*6)+(5*1)+(4*4)+(3*9)+(2*4)+(1*5)=97
97 % 10 = 7
So 6149-45-7 is a valid CAS Registry Number.
6149-45-7Relevant articles and documents
Mechanism of the Photochemical Wolff Rearrangement. The Role of Conformation in the Photolysis of α-Diazo Carbonyl Compounds.
Tomioka, Hideo,Okuno, Hiroshi,Izawa, Yasuji
, p. 5278 - 5283 (2007/10/02)
Investigation of photochemical processes of several α-diazo carbonyl compounds reveals that the Wolff rearrangement to form ketene takes place directly from the singlet excited state of the s-Z conformer whereas the excited state of the s-E conformer dissociates nitrogen to generate singlet carbonyl carbene, which either undergoes characteristic carbenic reactions, e.g., insertion and 1,2-hydrogen shift, or gives rise to ketene.The migratory aptitude as well as the relative efficiency of other competing reactions from singlet carbene is shown to be an important factor in dete rmining which reaction pathway is favored.Substantial amounts of singlet carbene can be formed even under sensitized conditions, presumably via intersystem crossing from initially formed triplet carbene.
