61517-87-1

Upstream product

• 501-36-0 (E)-5-[2-4-(hydroxyphenyl)ethenyl]-1,3-benzenediol 
• 870-63-3 prenyl bromide 
• 1269415-94-2 diethyl (4-((triisopropylsilyl)oxy)benzyl)phosphonate 
• 1269415-96-4 (E)-3,5-bis-methoxymethoxy-4'-triisopropylsilyloxystilbene 
• 1269416-00-3 (E)-3,5-dihydroxy-2-(3-methylbut-2-enyl)-40-triisopropylsilyloxystilbene 
• 76280-61-0 3,5-di-[(methoxymethyl)oxy]benzaldehyde 
• 930766-88-4 diethyl (4-(3-methyl-2-butenyl)-3,5-bis(methoxymethoxy)benzyl)phosphonate 
• 6515-21-5 4-methoxymethoxy-benzaldehyde 
• 1542214-54-9 4-prenyl-3,5,4′-tris(methoxymethoxy)-(E)-stilbene 
• 115-18-4 2-methyl-3-buten-2-ol 

Relevant academic research and scientific papers

Synthesis and evaluation of isoprenylation-resveratrol dimer derivatives against Alzheimer's disease

A series of resveratrol dimer derivatives against Alzheimer's disease (AD) was obtained by structural modification and transformation using resveratrol as substrate. Biological analysis revealed that these derivatives had moderate inhibitory activity agai

Stilbenes as κ-selective, non-nitrogenous opioid receptor antagonists

The natural stilbene pawhuskin A has been shown to function as an opioid receptor antagonist, with preferential binding to the κ receptor. This finding encouraged assembly of a set of analogues to probe the importance of key structural features. Assays on these compounds determined that one (compound 29) shows potent opioid receptor binding activity and significantly improved selectivity for the κ receptor. These studies begin to illuminate the structural features of these non-nitrogenous opioid receptor antagonists that are required for activity.

Total synthesis of chiricanine A, arahypin-1, trans -arachidin-2, trans -arachidin-3, and arahypin-5 from peanut seeds

The first and efficient syntheses of the naturally occurring prenylated stilbenes chiricanine A (2), arahypin-1 (3), trans-arachidin-2 (4), trans-arachidin-3 (5), and arahypin-5 (6) are described. Syntheses of 2 and 3 were accomplished by either a converg

Resveratrol Derivatives and Their Role as Potassium Channels Modulators

A series of stilbenoid analogues of resveratrol (trans-3,4′ ,5-trihydroxystilbene) with a stilbenic or a bibenzylic skeleton have been prepared by partial synthesis from resveratrol and dihydroresveratrol. The synthesized compounds have been evaluated for their ability to modulate voltage-gated channels.