615558-48-0

Upstream product

• 615558-47-9 3-(benzyloxy)-N-methoxy-N-methylbenzamide 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 99-06-9 3-Carboxyphenol 

Downstream Products

• 850056-55-2 3-(2-pyridinylmethyloxy)-N-methoxy-N-methylbenzamide 
• 84476-51-7 3-(4'-chlorobenzyloxy)-N-methoxy-N-methylbenzamide 
• 616196-26-0 N-methoxy-3-(methoxymethoxy)-N-methylbenzamide 
• 13020-57-0 3-hydroxybenzophenone 
• 103203-53-8 3-hydroxy-4'-methoxybenzophenone 
• 21084-29-7 4'-trifluoromethyl-3-hydroxy-benzophenone 
• 566899-68-1 (3-hydroxy-phenyl)-(3-methoxy-phenyl)-methanone 
• 103323-37-1 1-(3-hydroxy-phenyl)-2-methyl-propan-1-one 
• 62810-51-9 1-(3-hydroxyphenyl)pentan-1-one 

Relevant academic research and scientific papers

Enantioselective synthesis of 3-substituted dihydrobenzofurans through iridium-catalyzed intramolecular hydroarylation

Intramolecular hydroarylationviaC-H activation is one of the most powerful methods to synthesize carbo- and heterocyclic compounds, whereas we still have room for developing a highly enantioselective variant of the reaction. Here we describe Ir-catalyzed enantioselective intramolecular hydroarylation ofm-allyloxyphenyl ketones. The enantioselective cyclization was efficiently catalyzed by a cationic iridium complex coordinated with a conventional chiral bisphosphine ligand to give benzofurans in high yields with high enantioselectivity. A carbonyl group of ketones functioned as an effective directing group for the C-H activation. In terms of synthetic utility, we also achieved one-pot synthesis of chiral 3-substituted dihydrobenzofurans from readily available allylic carbonates andm-hydroxyacetophenonesviasequential Pd-catalyzed allylic substitution and Ir-catalyzed intramolecular hydroarylation.

NOVEL DIHYDROPYRIMIDIN-2(1H)-ONE COMPOUNDS AS S-NITROSOGLUTATHIONE REDUCTASE INHIBITORS

The present invention is directed to novel dihydropyrimidin-2(1H)-one compounds useful as S-nitrosoglutathione reductase (GSNOR) inhibitors, pharmaceutical compositions comprising such compounds, and methods of making and using the same.

Novel triarylimidazoles

Compounds of the general formula (I) are presented and are valuable therapeutics for the treatment of cancer and cancer related diseases.

2-(2,6-dichlorophenyl)-diarylimidazoles

The invention is directed to compounds of formula (I), which are valuable therapeutics for the treatment of cancer and related diseases.