62810-51-9Relevant articles and documents
Enantioselective synthesis of 3-substituted dihydrobenzofurans through iridium-catalyzed intramolecular hydroarylation
Nishimura, Takahiro,Sakamoto, Kana
, p. 684 - 690 (2021/02/06)
Intramolecular hydroarylationviaC-H activation is one of the most powerful methods to synthesize carbo- and heterocyclic compounds, whereas we still have room for developing a highly enantioselective variant of the reaction. Here we describe Ir-catalyzed enantioselective intramolecular hydroarylation ofm-allyloxyphenyl ketones. The enantioselective cyclization was efficiently catalyzed by a cationic iridium complex coordinated with a conventional chiral bisphosphine ligand to give benzofurans in high yields with high enantioselectivity. A carbonyl group of ketones functioned as an effective directing group for the C-H activation. In terms of synthetic utility, we also achieved one-pot synthesis of chiral 3-substituted dihydrobenzofurans from readily available allylic carbonates andm-hydroxyacetophenonesviasequential Pd-catalyzed allylic substitution and Ir-catalyzed intramolecular hydroarylation.
Suzuki-Miyaura coupling of simple ketones via activation of unstrained carbon-carbon bonds
Xia, Ying,Wang, Jianchun,Dong, Guangbin
supporting information, p. 5347 - 5351 (2018/05/03)
Here, we describe that simple ketones can be efficiently employed as electrophiles in Suzuki-Miyaura coupling reactions via catalytic activation of unstrained C-C bonds. A range of common ketones, such as cyclopentanones, acetophenones, acetone and 1-indanones, could be directly coupled with various arylboronates in high site-selectivity, which offers a distinct entry to more functionalized aromatic ketones. Preliminary mechanistic study suggests that the ketone α-C-C bond was cleaved via oxidative addition.
TETRAZOLINONE COMPOUND AND USE THEREOF
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, (2016/09/12)
A tetrazolinone compound represented by formula (1): wherein R1 and R2 each represents a hydrogen atom, a halogen atom, or a C1-C3 alkyl group; R3 represents a C1-C3 alkyl group optionally having one or more halogen atoms; R4, R5, and R6 each represents a hydrogen atom or a halogen atom; R7 represents a C1-C3 alkyl group; Q represents a divalent group selected from Group P4; and A represents a C7-C18 aralkyloxy group optionally having one or more atoms or groups selected from Group P3, has excellent control activity against pests.
CHEMICAL COMPOUNDS
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Page/Page column 54, (2008/06/13)
The present invention discloses novel compounds with a variety of therapeutic uses. More particularly, the invention discloses novel symmetrical triphenyl compounds that are particularly useful for selective estrogen receptor modulation.
CHEMICAL COMPOUNDS
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Page/Page column 30; 32; 39, (2008/06/13)
The present invention discloses to novel compounds with a variety of therapeutic uses. More particularly, the invention discloses novel symmetrical triphenyl compounds that are particularly useful for selective estrogen receptor modulation.
Preparation of m-acylphenol derivatives by the reaction of tricarbonyl(cyclohexadienone)iron complex and higher order cuprates
Ban, Sooho,Sakurai, Hidehiro,Hayashi, Yujiro,Narasaka, Koichi
, p. 699 - 700 (2007/10/03)
Reaction of tricarbonyl[(2,3,4,5-η)-2,4-cyclohexadien-1-one]iron and higher order cuprates followed by the treatment with acetic anhydride and then with carbon monoxide affords tricarbonyl[(1,2,3,4-η)-1-acetoxy-5-endo-acyl-1,3-cyclohexadiene]iron complexe