616241-13-5

Upstream product

• 36176-90-6 N-(4-bromobenzylidene)-4-methylbenzenesulfonamide 
• 78-94-4 methyl vinyl ketone 
• 254428-47-2 (E)-N-(4-bromobenzylidene)-4-methylbenzenesulfonamide 

Relevant academic research and scientific papers

Asymmetric catalytic aza-Morita-Baylis-Hillman reaction using chiral bifunctional phosphine amides as catalysts

The asymmetric catalytic aza-Morita-Baylis-Hillman reaction of N-sulfonated imines with α,β-unsaturated ketones has been successfully conducted by using chiral bifunctional phosphine amides as catalysts. A series of new chiral bifunctional phosphine amide

A Br?nsted acid and Lewis base organocatalyst for the aza-Morita-Baylis-Hillman reaction

(S)-3-[2-(Diphenylphosphino)phenyl]BINOL has been established as an efficient asymmetric bifunctional organocatalyst for the aza-Morita-Baylis- Hillman (aza-MBH) reaction. The Br?nsted acid and Lewis base functionalities cooperate in substrate activation

Asymmetric aza-Morita-Baylis-Hillman reaction of N-sulfonated imines with activated olefins catalyzed by chiral phosphine Lewis bases bearing multiple phenol groups

In the aza-Morita-Baylis-Hillman reaction of N-sulfonated imines (N-arylmethylidene-4-methyl-benzenesulfonamides) with methyl vinyl ketone (MVK), ethyl vinyl ketone (EVK), and acrolein, we found that, through the use of catalytic amounts of chiral phosphi

Bifunctional organocatalysts for enantioselective aza-Morita-Baylis-Hillman reaction

The efficient and novel bifunctional organocatalyst for the enantioselective aza-Morita-Baylis-Hillman (aza-MBH) reaction has been established with (S)-3-(N-isopropyl-N-3-pyridinylaminomethyl)BINOL for the first time. The reaction proved to be deeply infl

Conformational lock in a Bronsted acid-Lewis base organocatalyst for the aza-Morita-Baylis-Hillman reaction

(S)-3-(N-Isopropyl-N-3-pyridinylaminomethyl)BINOL has been established as an efficient asymmetric bifunctional organocatalyst for the aza-MBH reaction. The acid-base functionalities cooperate in substrate activation and fixing of the organocatalyst confor

Chiral phosphine Lewis base catalyzed asymmetric aza-Baylis-Hillman reaction of N-sulfonated imines with methyl vinyl ketone and phenyl acrylate

In the aza-Baylis-Hillman reaction of N-sulfonated imines with methyl vinyl ketone (MVK) promoted by chiral phosphine Lewis base: (R)-2′-diphenylphosphanyl-[1,1′]bi-naphthalenyl-2-ol (10 mol%), the aza-Baylis-Hillman adducts 1 were obtained in good yields

Chiral bifunctional organocatalysts bearing a 1,3-propanediamine unit for the aza-MBH reaction

The introduction of a 1,3-propanediamine unit at the 3-position of (S)-BINOL using a methylene spacer led to the formation of a chiral bifunctional organocatalyst for the aza-Morita-Baylis-Hillman (aza-MBH) reaction. The organocatalyst 1k mediated aza-MBH

A bifunctional spiro-type organocatalyst with high enantiocontrol: Application to the aza-Morita-Baylis-Hillman reactions

A unique spiro-type Bronsted acid-Lewis base organocatalyst has been developed. The new bifunctional organocatalyst promoted aza-Morita-Baylis- Hillman reactions to yield adducts with up to 98% ee.

Cooperativity in the counterion catalysis of Morita/Baylis/Hillman reactions promoted by enantioselective trifunctional organocatalysts

New trifunctional organocatalysts with a NHTs Br?nsted acid were prepared and tested in their ability to promote the counterion catalysis of generic and aza-Morita/Baylis/Hillman reactions.The cooperativity between the counterion and the NHTs Br?nsted aci

Trifunctional organocatalyst-promoted counterion catalysis for fast and enantioselective aza-Morita-Baylis-Hillman reactions at ambient temperature

Fast and enantioselective aza-Morita-Baylis-Hillman reactions between electron-deficient or electron-rich aromatic N-tosyl imines and methyl vinyl ketone were achieved at ambient temperature using asymmetric counterion-directed catalysis promoted by trifu