6164-78-9Relevant articles and documents
Nucleophically transformed N-heterocyclic nitriles trapped by cyanooxomolybdates(IV): Crystallographic and spectroscopic study
Ryniewicz, Anna,Tomecka, Monika,Szklarzewicz, Janusz,Matoga, Dariusz,Nitek, Wojciech
, p. 229 - 237,9 (2012)
The reaction of K3Na[Mo(CN)4O2] ·6H2O with 2,3-dicyanopyrazine or 2-pyridinecarbonitrile in aqueous media results in isolation of two new compounds of formulae (PPh 4)2[Mo(CN)3O(pzac)]·2H2O (Hpzac = 3-carbamoyl-2-pyrazinecarboxylic acid) and (PPh4) 2[Mo(CN)3O(pynccn)]·3H2O·EtOH (Hpynccn = 2-pyridineiminocarbonitrile) respectively. X-ray single crystal structure measurements as well as physicochemical measurements confirm transformations of 2,3-dicyanopyrazine to 3-carbamoyl-2-pyrazinecarboxylic acid and 2-pyridinecarbonitrile to 2-pyridineiminocarbonitrile. All complexes are characterized by elemental analysis, IR and UV-Vis spectroscopy. Metal-assisted ligand transformations are studied spectrophotometrically in the pH range 8.5-11.5. Two different pathways of nitrile reactivity are shown and discussed.
One-step Preparation of 3-Alkoxypyrazine-2-carbonitriles from Pyrazine-2,3-dicarbonitriles and Related Reactions
Kojima, Takakazu,Nagasaki, Fumihiko,Ohtsuka, Yozo
, p. 455 - 459 (2007/10/02)
A series of 5,6-disubstituted 3-alkoxypyrazine-2-carbonitriles (2a-i) were prepared from 5,6-disubstituted pyrazine-2,3-dicarbonitriles (1a-d) by direct substitution with alcohols.Treatment of 1 with amines gave either pyrrolopyrazines (3a,b) or substitution products (4,5).In a low temperature range, 1 afforded imidates and related compounds (6-11).The preference among these reactions depended on the 5,6-substituents and on the reaction conditions.
