6165-51-1

Basic information

• Product Name: 2-(1-phenylethyl)-p-xylene
• Synonyms: 2-(1-phenylethyl)-p-xylene;1,4-DIMETHYL-2-(PHENYLETHYL)BENZENE;(1-PHENYLETHYL)(DIMETHYL)BENZENE;1,4-Dimethyl-2-(1-phenylethyl)benzene;1,4-Dimethyl-2-(α-methylbenzyl)benzene;2-(α-Methylbenzyl)-p-xylene
• CAS NO: 6165-51-1
• Molecular Formula: C16H18
• Molecular Weight: 210.31412
• EINECS: 228-201-0
• Mol File: 6165-51-1.mol
• Article Data: 24

Chemical Properties

• Melting Point: 102-103 °C
• Boiling Point: 302.3°C at 760 mmHg
• Flash Point: 139.8°C
• Appearance: /
• Density: 0.961g/cm³
• Vapor Pressure: 0.00179mmHg at 25°C
• Refractive Index: 1.551
• CAS DataBase Reference: 2-(1-phenylethyl)-p-xylene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-phenylethyl)-p-xylene(6165-51-1)
• EPA Substance Registry System: 2-(1-phenylethyl)-p-xylene(6165-51-1)

Safety Data

• Hazardous Substances Data: 6165-51-1(Hazardous Substances Data)

Usage

General Description

2-(1-phenylethyl)-p-xylene is an organic compound that belongs to the class of chemicals known as xylene isomers. It is a derivative of xylene, which is a common solvent and precursor for various industrial chemicals. The structure of 2-(1-phenylethyl)-p-xylene includes a phenylethyl group attached to the para position of the xylene molecule. This chemical has a variety of industrial applications, including its use as a solvent in coatings, adhesives, and sealants. It is also used in the production of rubber, plastics, and other chemical intermediates. Additionally, 2-(1-phenylethyl)-p-xylene may be used in the synthesis of pharmaceuticals and other fine chemicals. Despite its usefulness, it is important to handle this chemical with caution due to its potential health and environmental hazards.

InChI:InChI=1/C16H18/c1-12-9-10-13(2)16(11-12)14(3)15-7-5-4-6-8-15/h4-11,14H,1-3H3

Upstream product

• 100-42-5 styrene 
• 106-42-3 para-xylene 
• 98-85-1 1-Phenylethanol 
• 1517-69-7 (R)-1-phenylethanol 
• 553-94-6 4-bromo-m-xylene 
• 98-86-2 acetophenone 
• 1524-12-5 1-phenylethyl 2,2,2-trifluoroacetate 
• 585-71-7 (1-bromoethyl)benzne 
• 729-43-1 acetophenonazine 
• 93-92-5 1-phenylethyl acetate 

Downstream Products

• 573-69-3 benzophenone-2,5-dicarboxylic acid 

Relevant articles and documents

Multifunctional oxygen vacancies in WO3–x for catalytic alkylation of C–H by alcohols under red-light

Surface reaction kinetics and light absorption properties of a photocatalyst are essential demands for efficiently solar to chemical energy converting. In this study, plasmonic WO3–x was firstly applied to photocatalytic alkylation of arenes under red light irradiation. The oxygen vacancies, both on the surface and in the bulk of WO3–x, allow abundant free electrons to increase carrier densities and support its LSPR using low energy photons. The surface oxygen vacancies have more functions: they not only release surface tungsten sites which ensure the chemisorption of alcohols due to the coordianation ability but also promote the activation of alcohols via an efficient transport of the holes on the neighbouring O sites to chemisorption alcohol species. In brief, the bulk oxygen vacancies provide abundant charges and the surface vacancies promote the bond adsorption and activation abilities, which ensure the high efficiency of photocatalytic alkylation of C–H.

Bisulfate Salt-Catalyzed Friedel-Crafts Benzylation of Arenes with Benzylic Alcohols

We report here a method of direct Friedel-Crafts benzylation of arenes with benzylic alcohols using cheap and readily available bisulfate salt as the catalyst in hexafluoroisopropanol. The catalytic system is powerful with a quite diverse group of functionalized arenes and benzylic alcohols. These mild conditions provide a straightforward synthesis of a variety of unsymmetrical diarylmethanes in high yield with good to high regioselectivity. An SN1 mechanism involving activation of the hydroxy group through a hydrogen bond is proposed.

Hydroarylation of styrenes with electron-rich arenes over acidic ion-exchange resins

A series of acidic cation-exchange resins were used for the hydroarylation of resorcinol with styrene, in which resin D072 exhibited the excellent catalytic performance in this reaction with 99% conversion of styrene and 90% selectivity of 4-(1-phenylethyl)resorcinol. It was applied to the hydroarylation of various electron-rich arenes with styrenes, and the hydroarylated products were quantitatively obtained. This catalyst could be used for four consecutive runs with slight decrease in activity. The hydroarylation of resorcinol with styrene over resin D072 in a fixed bed was completed effectively with 94% selectivity and 99% conversion, and this green continuous process is potentially applicable to large-scale productions.