6170-23-6 Usage
Formation
Salt formed by reaction of 2-aminopropan-1-ol with hydrochloric acid
Uses
Reagent in organic synthesis and pharmaceutical research
Physical properties
Colorless, odorless solid at room temperature; highly soluble in water
Biological activities
Anti-inflammatory and analgesic properties
Applications
Production of pharmaceutical drugs; potential treatment for medical conditions
Check Digit Verification of cas no
The CAS Registry Mumber 6170-23-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,7 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 6170-23:
(6*6)+(5*1)+(4*7)+(3*0)+(2*2)+(1*3)=76
76 % 10 = 6
So 6170-23-6 is a valid CAS Registry Number.
InChI:InChI=1/C3H9NO.ClH/c1-3(4)2-5;/h3,5H,2,4H2,1H3;1H
6170-23-6Relevant articles and documents
Radical-mediated intramolecular β-C(sp3)-H amidation of alkylimidates: Facile synthesis of 1,2-amino alcohols
Mou, Xue-Qing,Chen, Xiang-Yu,Chen, Gong,He, Gang
supporting information, p. 515 - 518 (2018/01/19)
A new radical-mediated intramolecular β-C(sp3)-H amidation reaction of O-alkyl trichloro- or arylimidates is reported. Various oxazolines were efficiently prepared from easily accessible alcohol starting materials. The trichloro-oxazoline products can be hydrolyzed under mild conditions to give valuable 1,2-amino alcohols. This amidation reaction exhibits a broad substrate scope and good functional group tolerance, and offers a powerful means for the C(sp3)-H functionalization of alcohols. Mechanistic studies suggest that a sequence of 1,5-HAT of an imidate radical, iodination and cyclization might be operative.
