61702-15-6

Basic information

• Product Name: 4-PROPYL-PYRIDIN-2-YLAMINE
• Synonyms: 2-AMINO-4-PROPYL PYRIDINE;4-PROPYL-PYRIDIN-2-YLAMINE;4-propylpyridin-2-aMine
• CAS NO: 61702-15-6
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19
• Mol File: 61702-15-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 257.4 °C at 760 mmHg
• Flash Point: 133.2 °C
• Appearance: /
• Density: 1.014 g/cm³
• Vapor Pressure: 0.0146mmHg at 25°C
• Refractive Index: 1.549
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: 4-PROPYL-PYRIDIN-2-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-PROPYL-PYRIDIN-2-YLAMINE(61702-15-6)
• EPA Substance Registry System: 4-PROPYL-PYRIDIN-2-YLAMINE(61702-15-6)

Safety Data

• Hazardous Substances Data: 61702-15-6(Hazardous Substances Data)

Usage

General Description

4-Propyl-pyridin-2-ylamine is a chemical compound with the molecular formula C10H14N2. It is a derivative of pyridine and contains a propyl group attached to the second position of the pyridine ring. 4-PROPYL-PYRIDIN-2-YLAMINE is commonly used in pharmaceutical research and drug development due to its potential biological activities. It has been studied for its potential as a treatment for various medical conditions, including cancer, central nervous system disorders, and inflammation. Additionally, 4-propyl-pyridin-2-ylamine has been investigated for its role in modulating neurotransmitter function in the brain, making it a promising candidate for drug development in the field of neuroscience.

InChI:InChI=1/C8H12N2/c1-2-3-7-4-5-10-8(9)6-7/h4-6H,2-3H2,1H3,(H2,9,10)

Upstream product

• 1122-81-2 4-n-propylpyridine 
• 30838-95-0 2-chloro-4-propylpyridine 
• 663614-88-8 4-n-propyl-2-pyridinecarbonitrile 
• 25813-87-0 4-propylpyridine-1-oxide 

Downstream Products

• 1418307-29-5 (S)-4-(8-methyl-3-(piperidin-2-yl)imidazo[1,5-a]pyrazin-1-yl)-N-(4-propylpyridin-2-yl)benzamide 
• 1418307-28-4 (S)-benzyl 2-(8-methyl-1-(4-(4-propylpyridin-2-ylcarbamoyl)phenyl)imidazo[1 ,5-a]pyrazin-3-yl)piperidine-1-carboxylate 
• 1418307-27-3 N-(4-propylpyridin-2-yl)-4-(4,4,5,5-tetramethyl-1 ,3,2-dioxaborolan-2-yl)benzamide 
• 87999-87-9 4-propyl-pyridine-2-carboxylic acid 

Relevant articles and documents

QUINOLINE AND QUINAZOLINE COMPOUNDS

In some embodiments, the invention relates to quinazoline and quinoline compounds of Formula I: (I) or a pharmaceutically acceptable salt thereof, or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, in some embodiments, the present invention relates to quinazoline and quinoline compounds, pharmaceutical compositions thereof, and the use of the compounds and pharmaceutical compositions in the treatment of Bruton's tyrosine kinase (BTK) mediated disorders.

INHIBITORS OF BRUTON'S TYROSINE KINASE

Disclosed herein are compounds that form covalent bonds with Bruton's tyrosine kinase (Btk). Also described are irreversible inhibitors of Btk. In addition, reversible inhibitors of Btk are also described. Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are disclosed, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.

Substituted 2-aminopyridines as inhibitors of nitric oxide synthases.

A series of substituted 2-aminopyridines was prepared and evaluated as inhibitors of human nitric oxide synthases (NOS). 4,6-Disubstitution enhanced both potency and specificity for the inducible NOS with the most potent compound having an IC50 of 28 nM.