61707-79-7

Basic information

• Product Name: Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate
• Synonyms: Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate;Methyl 4-oxo-1,4-dihydroquinoline-3-carboxylate
• CAS NO: 61707-79-7
• Molecular Formula: C₁₁H₉NO₃
• Molecular Weight: 203.19406
• EINECS: -0
• Mol File: 61707-79-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 228 °C
• Boiling Point: 331.1±42.0 °C(Predicted)
• Appearance: /
• Density: 1.288±0.06 g/cm3(Predicted)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 1.02±0.70(Predicted)
• CAS DataBase Reference: Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate(61707-79-7)
• EPA Substance Registry System: Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate(61707-79-7)

Safety Data

• Hazardous Substances Data: 61707-79-7(Hazardous Substances Data)

Usage

General Description

Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate is a chemical compound with the molecular formula C12H11NO3. It is a derivative of quinoline, a heterocyclic aromatic compound with a nitrogen atom in the ring. Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate is commonly used in organic synthesis and pharmaceutical research due to its potential biological activities. It is also known for its antimicrobial, anticancer, and antiviral properties. Methyl 4-oxo-1,4-dihydro-3-quinolinecarboxylate is often used as a building block in the synthesis of various drugs and pharmaceutical compounds.

Upstream product

• 133514-20-2 1-Acetyl-1,2-dihydro-4-hydroxy-quinoline-3-carboxylic acid methyl ester 
• 3377-21-7 dimethyl 2-methylenemalonate 
• 22398-14-7 dimethyl (methoxymethylene)malonate 
• 62-53-3 aniline 
• 38238-86-7 dimethyl 2-phenylaminoethylene-1,1-dicarboxylate 
• 133514-26-8 2-[Methoxycarbonyl-(2-methoxycarbonyl-ethyl)-amino]-benzoic acid methyl ester 
• 62985-19-7 methyl 3-propanoate 
• 38113-64-3 methyl 3-(o-methoxycarbonylanilino)propionate 
• 251986-52-4 4,5-dimethoxycarbonyl-1-phenyl-1H-pyrrole-2,3-dione 
• 61707-70-8 dimethyl 4-oxo-1,4-dihydroquinoline-2,3-dicarboxylate 
• 4916-29-4 dimethyl 2-(phenyl-amino)-2-butendioate 
• 61707-75-3 3-methoxycarbonyl-4-quinolone-2-carboxylic acid 
• 133530-05-9 1-Methoxycarbonyl-1,2-dihydro-4-hydroxy-quinoline-3-carboxylic acid methyl ester 

Downstream Products

• 13721-01-2 4-oxo-1,4-dihydroquinoline-3-carboxylic acid 
• 1353669-36-9 methyl 1-benzyl-4-oxo-1,4-dihydroquinoline-3-carboxylate 
• 35975-86-1 1-benzyl-1,4-dihydro-4-oxoquinoline-3-carboxylic acide 
• 338747-41-4 1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid 

Relevant articles and documents

Novel quinolin-4(1H)-one derivatives as multi-effective aldose reductase inhibitors for treatment of diabetic complications: Synthesis, biological evaluation, and molecular modeling studies

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Quinolone-based compounds, formulations, and uses thereof

Provided herein are quinolone-based compounds that can be used for treatment and/or prevention of malaria and formulations thereof. Also provided herein are methods of treating and/or preventing malaria in a subject by administering a quinolone-based compound or formulation thereof provided herein.

A synthesis of 4-quinolone-3-carboxylic acids via pyrolysis of N- aryldioxopyrrolines

A synthesis of 4-quinolone-3-carboxylic acids (8) was achieved by pyrolysis of 4,5-dimethoxycarbonyl-1-aryl-1H-pyrrole-2,3-diones (3) followed by selective demethoxycarbonylation of the resulting 2,3-dimethoxycarbonyl-4- quinolones (4) in excellent overall yields.