61715-97-7Relevant academic research and scientific papers
Facile synthesis of 8-azido-6-benzylaminopurine
Steklov, Mikhail Yu.,Tararov, Vitali I.,Romanov, Georgy A.,Mikhailov, Sergey N.
, p. 503 - 511 (2011/12/21)
Bromination of 6-benzylaminopurine (1) with Br2 in AcOH in the presence of AcONa afforded 6-benzylamino-8-bromopurine (2) in 59% yield. The position of bromination was confirmed by direct transformation of bromide 2 by reaction with NaN3 in dimethyl sulfoxide to 8-azido-6-benzylaminopurine (3) in a yield of 70% and comparison of its properties with the known compound 2-azido-6- benzylaminopurine (11). Compounds 3 and 11 were checked for their biological activity in specific biotests based on the primary cytokinin effects in living plants. Both synthesized compounds displayed effects similar to the typical cytokinin 6-benzylaminopurine (1). Copyright Taylor and Francis Group, LLC.
