61751-33-5Relevant academic research and scientific papers
Reaction of secondary and tertiary aliphatic halides with aromatic aldehydes mediated by chromium(II): a selective cross-coupling of alkyl and ketyl radicals
Wessjohann, Ludger A.,Schmidt, Gisela,Schrekker, Henri S.
, p. 2134 - 2142 (2008/09/18)
Takai-Utimoto reactions with secondary and tertiary aliphatic halides usually failed according to previous reports. Now, significant improvements could be achieved, and especially secondary aliphatic halides can be coupled to aromatic aldehydes in yields of up to >95%. A variety of processes are competing with the desired one, and thus conditions must be adapted to the nature of the aldehyde as well as the aliphatic halide used, as the outcome of these reactions is strongly affected by the putative radical intermediates.
Influence of Alkyl Chain Ramification on Estradiol Receptor Binding Affinity and Intrinsic Activity of 1,2-Dialkylated 1,2-Bis(4- or 3-hydroxyphenyl)ethane Estrogens and Antiestrogens
Hartmann, Rolf W.
, p. 1668 - 1674 (2007/10/02)
The influence of a symmetrical introduction of CH3 substituents in the α or β positions of the 1,2-dialkyl-1,2-bis(4-hydroxyphenyl)ethene estrogens hexestrol (ethyl, HES) and octestrol (n-propyl, OCES) isopropyl (1), tert-butyl (2), sec-butyl (3), isobut
Novel di-(3'-hydroxyphenyl)-alkane compounds, process of preparation and their use in medicine
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, (2008/06/13)
Compounds of di-(3'-hydroxyphenyl)-alkanes and their methyl ethers, of the formula STR1 wherein R is alkyl and R' is H or methyl, have activity against hormone-dependent breast carcinoma.
