6178-58-1

Upstream product

• 96-09-3 styrene oxide 
• 108-98-5 thiophenol 
• 51256-38-3 methyl α-phenyl-α-(phenylthio)acetate 
• 882-33-7 diphenyldisulfane 
• 139058-68-7 (+/-)-1,1-diacetoxy-2-phenyl-2-(phenylsulphenyl)ethane 
• 10490-07-0 2-phenyl-2-(phenylthio)acetic acid 
• 50-00-0 formaldehyd 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 100-52-7 benzaldehyde 
• 930-69-8 sodium thiophenolate 
• 1449477-04-6 (phenylsulfenyl)zinc bromide 
• 28074-23-9 phenylsulfenyl bromide 
• 611-71-2 MANDELIC ACID 
• 2912-62-1 α-chlorophenylacetyl chloride 

Downstream Products

• 33169-42-5 2-phenyl-2-(phenylsulfonyl)ethan-1-ol 
• 1608154-14-8 2-phenyl-2-(phenylthio)ethyl acrylate 
• 1021297-32-4 2-phenyl-2-phenylthioethyl methacrylate 
• 65885-17-8 C₁₆H₁₈O₃S 
• 29290-75-3 C₂₀H₁₈O₂S₂ 
• 65885-24-7 Acetic acid 2-benzenesulfonyl-2-phenyl-ethyl ester 
• 49833-39-8 α-phenyl vinyl phenylsulfone 
• 65885-25-8 Methanesulfonic acid 2-benzenesulfonyl-2-phenyl-ethyl ester 
• 65885-23-6 C₁₄H₁₃BrO₂S 
• 65885-22-5 C₁₄H₁₃ClO₂S 
• 53876-79-2 1,2-bis-benzenesulfonyl-1-phenyl-ethane 

Relevant academic research and scientific papers

Synthesis and application of Cu(II) immobilized MCM-41 based solid Lewis acid catalyst for aminolysis reaction under solvent-free condition

In this paper, a Cu(II) immobilized periodic mesoporous organosilica (PMOs) was synthesized and used as a reusable solid Lewis acid catalyst for the aminolysis of epoxides under solvent-free conditions. An amide-based ligand, L-propylsilyl (1) having a specific binding pocket was prepared and fabricated on mesoporous MCM-41 to produce mesoporous organosilica L-propylsilyl@MCM-41 (2). Further, it has been utilized for anchoring Cu(II) ions under controlled reaction conditions to yield solid Lewis acid catalyst Cu(II)-L-propylsilyl@MCM-41 (3). The synthesized catalyst 3 exhibits significantly higher catalytic activity for aminolysis compared to hitherto known solid Lewis acid catalysts. An extensive range of β-amino alcohols with high regio and stereoselectivity were prepared by using catalyst 3. The catalyst was recovered easily and reused eight times without any loss in its catalytic activity. Furthermore, the synthesis of clinically significant propranolol (β-blocker) from α- naphthyl glycidyl ether was attained successfully using catalyst 3 in a very decent yield.

Umpolung Difunctionalization of Carbonyls via Visible-Light Photoredox Catalytic Radical-Carbanion Relay

The combination of photoredox catalysis with the Wolff-Kishner (WK) reaction allows the difunctionalization of carbonyl groups by a radical-carbanion relay sequence (photo-Wolff-Kishner reaction). Photoredox initiated radical addition to N-sulfonylhydrazones yields α-functionalized carbanions following the WK-type mechanism. With sulfur-centered radicals, the carbanions are further functionalized by reaction with electrophiles including CO2 and aldehydes, whereas CF3 radical addition furnishes a wide range of gem-difluoroalkenes through β-fluoride elimination of the generated α-CF3 carbanions. More than 80 substrate examples demonstrate the broad applicability of this reaction sequence. A series of investigations including radical inhibition, deuterium labeling, fluorescence quenching, cyclic voltammetry, and control experiments support the proposed radical-carbanion relay mechanism.

Biodegradable choline hydroxide promoted environmentally benign thiolysis of epoxides

An environmentally benign and rapid thiolysis of epoxides using a biodegradable, choline-based task-specific ionic liquid has been developed. The ring opening reaction of aryl and alkyl epoxides proceeded rapidly and afforded the corresponding β-hydroxysulfides in high yields with excellent regioselectivity. The protocol has the advantages of easy work-up, short reaction times, high yields, and a biodegradable catalyst.

Addition of unactivated thiols to epoxides and oxetanes catalyzed by a rhenium-oxo complex

A method for synthesizing β- and γ-hydroxy thioethers via addition of unactivated thiols to epoxides and oxetanes has been developed. This reaction is proposed to proceed through an unconventional mode of activation of the heterocycles. The transformation is catalyzed by ReO2I(PPh 3)2 affording β- and γ-hydroxy thioethers in moderate to excellent yield with excellent regioselectivity.

SULPHUR CONTAINING HIGH REFRACTIVE INDEX MONOMER

This invention discloses aromatic based sulfur containing hydrophobic acrylate monomer with high refractive index. The invention further discloses process for the preparation of 2-phenyl-2-(phenylthio)ethyl acrylate of the formula (I). This monomer can be

Synthesis and evaluation of sulfonylethyl-containing phosphotriesters of 3′-azido-3′-deoxythymidine as anticancer prodrugs

A series of bis(sulfonylethyl) and mono(sulfonylethyl) phenyl phosphotriesters of zidovudine (3′-azido-3′-deoxythymidine, AZT) were synthesized as potential anticancer prodrugs that liberate AZT monophosphate via nonenzymatic β-elimination mechanism. Stab

Rapid, benign, and additive-free thiolysis of epoxides under ultrasonic/aqueous conditions

An environmentally friendly and efficient procedure is developed for ring opening of various epoxides with thiols under non-thermal conditions. Reactions take place by ultrasonic irradiation of the two reactants suspended in an additive-free aqueous mediu

In situ slow release of isocyanates: Synthesis and organocatalytic application of N-acylureas

A novel, efficient, and operationally simple one-pot synthesis of both, symmetrical and unsymmetrical N-acylureas from carboxamides and in situ generated isocyanates (from N,N-dibromo-p-toluenesulfonamide) in the presence of a mild base at rt is reported. The protocol avoids the tedious isolation and purification steps of hazardous isocyanates. The first application of these acylureas to the catalysis through hydrogen bonding is also demonstrated.

" On-water " thiolysis of epoxides promoted by PhSZnBr

The synthesis of a new bench-stable and odorless zinc thiolate is here reported. The thiolysis of epoxides effected using this reagent showed a considerable rate acceleration of the reaction when effected in "on-water" conditions. In addition, the reactio

Kinetic resolution of α-bromophenylacetamides using quinine or Cinchona alkaloid salts

The kinetic resolution of racemic α-bromophenylacetamides 1 was achieved in the presence of benzenethiolate and Cinchona alkaloid salts as phase-transfer catalysts or benzenethiol and quinine, yielding (S)-enantioenriched α-sulfanylated products. The observed stereoselection was rationalized on the basis of the best fitting of 1 and the resolving agent in the ternary complexes.