618-05-3

Upstream product

• 585-43-3 2-allyl-5-trifluoromethyl phenol 
• 98-17-9 3-Trifluoromethylphenol 
• 585-49-9 1-(prop-2-en-1-yloxy)-3-(trifluoromethyl)benzene 

Downstream Products

• 1629184-55-9 2-(allyloxy)-1-propyl-4-(trifluoromethyl)benzene 
• 1629184-56-0 2-allyl-6-propyl-3-(trifluoromethyl)phenol 
• 448-36-2 2-methoxy-4-(trifluoromethyl)-benzoic acid 
• 582-14-9 2-propyl-5-trifluoromethyl-anisole 

Relevant academic research and scientific papers

A transition-metal-free synthesis of fluorinated naphthols

Herein, we describe a transition-metal-free protocol for the conversion of simple 2-allyl-3-(trifluoromethyl)phenols into substituted 5-fluoronaphthalen-1- ols. The key events of this reaction include the selective activation of two C-F bonds and formatio

NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.