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Usage

Uses

Used in Fragrance Industry:
Ethyl methyl propanedioate is used as a fragrance ingredient for its fruity, floral scent, adding a pleasant aroma to various products such as perfumes, soaps, and cosmetics.
Used in Flavoring Industry:
Ethyl methyl propanedioate is utilized as a flavoring agent, imparting a sweet, berry-like taste to food and beverage products, enhancing their overall flavor profile.
Used in Artificial Flavorings Production:
Ethyl methyl propanedioate is employed in the production of artificial flavorings, contributing to the development of unique and desirable tastes in a wide range of applications.
Used in Industrial Processes as a Solvent:
Ethyl methyl propanedioate serves as a solvent in various industrial processes, facilitating reactions and improving the efficiency of manufacturing operations.
It is crucial to handle ethyl methyl propanedioate with caution, as it can pose health risks if ingested or inhaled in large amounts. Proper safety measures should be taken to minimize potential hazards during its use.

Upstream product

• 6626-84-2 dimethyl 2-benzylidenepropanedioate 
• 105-56-6 ethyl 2-cyanoacetate 
• 67-56-1 methanol 
• 1010117-23-3 diethyl 2-nitro-3-oxopentanedioate 
• 627-93-0 hexanedioic acid dimethyl ester 
• 105-53-3 diethyl malonate 
• 64-17-5 ethanol 
• 687-00-3 methyl 4,4,4-trichloroacetoacetate 

Downstream Products

• 97985-81-4 methyl ethyl (phenylimino)malonate 
• 25816-60-8 3-oxo-3H-naphtho[2,1-b]pyran-2-carboxylic acid methyl ester 
• 2049-80-1 (2-propenyl)propanedioic acid diethyl ester 
• 1190384-60-1 ethyl methyl diallyl malonate 
• 15785-08-7 2-methyl-3-carbethoxyquinoline 
• 76311-95-0 methyl 3-(methylamino)-3-oxopropanoate 
• 33323-10-3 2-methyl-5-oxo-4-(4-hydroxyphenyl)-1,4,5,6,7,8-hexahydroquinoline-3-carboxylic acid ethyl ester 
• 1169983-38-3 4-(2-chloro-phenyl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-quinoline-3-carboxylic acid ethyl ester 
• 33323-05-6 ethyl 4-(4-chlorophenyl)-2-methyl-5-oxo-1,4,6,7,8-pentahydroquinoline-3-carboxylate 
• 5452-39-1 3-acetyl-8-methoxy-2H-chromen-2-one 
• 3949-36-8 3-acetylcoumarin 
• 59081-26-4 6-methoxy-2-phenylpyrimidin-4-ol 
• 1253791-97-7 C₁₇H₁₅N₃O₄S 
• 1405680-10-5 (±)-1-ethyl 3-methyl 2-(3-oxo-1-phenyl-3-(phenylamino)propyl)malonate 

Relevant academic research and scientific papers

One-by-one hydrogenation, cross-coupling reaction, and Knoevenagel condensations catalyzed by PdCl2 and the downstream palladium residue

A novel catalyst-economic strategy with a recovered palladium catalyst was successfully applied for multi-task and maximum reuse in different types of one-by-one downstream reactions, from catalytic hydrogenation to Suzuki and Sonogashira-type cross-coupling reactions, Knoevenagel condensations, and trans-Knoevenagel-like condensations.

Nucleophilic substitution accompanying carbon-carbon bond cleavage assisted by a nitro group

A 2-nitrated 3-oxoester reacted with amines or alcohols to afford unsymmetrical malonic acid derivatives as a result of nucleophilic substitution accompanying C-C bond cleavage. The 2-nitrated 3-oxoester easily formed ammonium salts with amines. When the amine is liberated from the salt under equilibrium, nucleophilic amine and electrophilic keto ester locate close to each other. This intimate pair effect causes a pseudo intramolecular reaction to occur, giving rise to effective substitution under mild conditions.

Synthesis of 2/6-(polychloromethyl)pyridinecarboxylates

Due to their relationship to certain bio-active 2,6-(polyfluoromethyl)-3,5-pyridinedicarboxylates 12, methodology was developed to prepare new, but analogous 2/6 (polychloromethyl)pyridinecarboxylates 6, 9, 10, 13, 18 and 20.Successful methods to prepare these materials include several chlorination procedures, mixed Hantzsch sequences, and aluminium chloride interchanges with 12 and 16.

ALKYLCOBALT CARBONYLS. VI. REACTION OF COBALT TETRACARBONYL WITH I2 DISSOLVED IN MeOH

Reaction of EtOOCCH2Co(CO)4 with I2 dissolved in MeOH yields XCH2COOEt (X=H, I, COOMe): the product with X=COOMe was formed even in the reaction in Ar.

A FACILE METHOD OF TRANSESTERIFICATION USING PHOSPHORUS YLID

The transesterification of carboxylic esters catalysed with phosphorus ylid under neutral and mild conditions has been investigated.The reactions of esters having an electron withdrawing group with methanol proceeded rapidly and with high yield, whereas the reverse reactions proceeded slowly or not at all.