61864-67-3

Upstream product

• 1122-62-9 2-acetylpyridine 
• 1122-91-4 4-bromo-benzaldehyde 
• 1121-60-4 pyridine-2-carbaldehyde 
• 99-90-1 para-bromoacetophenone 
• 586-76-5 4-Bromobenzoic acid 

Downstream Products

• 1197386-15-4 2-(p-tolylthio)-4-(4-bromophenyl)-6-(pyridin-2-yl)pyridine-3-carbonitrile 
• 89972-76-9 4'-(4-bromo-phenyl)-[2,2';6',2'']terpyridine 

Relevant academic research and scientific papers

Substituted 2,4-Di(pyridin-2-yl)pyrimidine-Based Ruthenium Photosensitizers for Hydrogen Photoevolution under Red Light

The photocatalytic reduction of water to form hydrogen gas (H2) is a promising approach to collect, convert, and store solar energy. Typically, ruthenium tris(bipyridine) and its many derivatives are used as photosensitizers (PSs) in a variety of photocatalytic conditions. The bis(terpyridine) analogues, however, have only recently gained attention for this application because of their poor photophysical properties. Yet, by the introduction of electron-donating or -withdrawing groups on the terpyridine ligands, the photophysical and electrochemical properties can be considerably improved. In this study, we report a series of nonsymmetric 2,6-di(pyridin-2-yl)pyrimidine ligands with peripheral pyridine substituents in different positions and their corresponding ruthenium(II) complexes. The presence of the pyrimidine ring stabilizes the lowest unoccupied molecular orbital, leading to a red-shifted emission and prolonged excited-state lifetimes as well as higher luminescence quantum yields compared to analogous terpyridine complexes. Furthermore, all complexes are easier to reduce than the previously reported bis(terpyridine) complexes used as PSs. Interestingly, the pyridine substituent in the 4-pyrimidine position has a greater impact on both the photophysical and electrochemical properties. This correlation between the substitution pattern and properties of the complexes is further investigated by using time-dependent density functional theory. In hydrogen evolution experiments under blue- and red-light irradiation, all investigated complexes exhibit much higher activity compared to the previously reported ruthenium(II) bis(terpyridine) complexes, but none of the complexes are as stable as the literature compounds, presumably because of an additional decomposition pathway of the reduced PS competing with electron transfer from the reduced PS to the catalyst.

Synthesis, characterization and biological application of pyrazolo[1,5-a]pyrimidine based organometallic Re(I) complexes

The neutral rhenium(I) complexes (I-VI) of type [ReCl(CO)3Ln] {where L1 = 7-phenyl-5-(pyridin-2-yl)pyrazolo[1,5-a] pyrimidine, L2 = 7-(4-bromophenyl)-5-(pyridin-2-yl)pyrazolo[1,5-a]pyrimi- dine, L3 =

Design and development of a heterogeneous catalyst for the michael addition of malononitrile to 2-enoylpyridines: Influence of the primary amide decorated framework on catalytic activity and selectivity

For the Michael addition of malononitrile to 2-enoylpyridines, we report the first heterogeneous catalyst, {[Zn2(2-bpbg)(fum)2]·4H2O·EtOH}n (1) (where 2-bpbg = N,N′-bis(2-pyridylmethyl)-1,4-diaminobutane-N,N′-di

Synthesis and characterization of a new ditopic bipyridine-terpyridine bridging ligand using a Suzuki cross-coupling reaction

Synthesis of a new bridging ligand 4'-{4-[(2,2'-bipyridin)-4-yl]-phenyl}-2,2':6'-2''-terpyridine (I) was reported. A Suzuki cross-coupling reaction was conducted for the preparation of such ligand in two different routes either between 4'-(4-bromophenyl)-2,2':6'-2''-terpyridine and 2,2'-bipyridyl-4-boronic acid or 4'-(4-boronatophenyl)-2,2':6',2''-terpyridine and 4-bromo-2,2'-bipyridine. Br HO OH B + N N N N N N N HO OH B Br N + N N N (I) N N N N

Isomeric spiro-[acridine-9,9′-fluorene]-2,6-dipyridylpyrimidine based TADF emitters: Insights into photophysical behaviors and OLED performances

TADF molecules with a higher horizontal-dipole ratio have recently been realized to show a large conversion efficiency in organic light-emitting diodes (OLEDs) and hence great promise for their application in display and solid state lighting sources. The

Halo-substituted chalcones and azachalcones-inhibited, lipopolysaccharited-stimulated, pro-inflammatory responses through the TLR4-mediated pathway

A series of B-ring, halo-substituted chalcones and azachalcones were synthesized to evaluate and compare their anti-inflammatory activity. Mouse BALB/c macrophage RAW 264.7 were pre-treated with 10 μg/mL of each compound for one hour before induction of i

Half Sandwich Rhodium(III) and Iridium(III) Complexes as Cytotoxic and Metallonuclease Agents

Half sandwich complexes of the type [(η5-C5Me5)M(L1–3)Cl]Cl.2H2O were synthesized using [{(η5-C5Me5)M(μ-Cl)Cl}2], where M = Rh(III)/Ir(III) and L1–3 = pyrim

Intramolecular C-N bond formation under metal-free conditions: Synthesis of indolizines

Polysubstituted indolizine derivatives are constructed via intramolecular C-N bond formation/C-H bond cleavage under metal-free conditions. These methods offer straightforward pathways to transform pyridyl chalcones into a variety of indolizines.

Diastereo- and enantioselective direct vinylogous Michael addition of γ-substituted butenolides to 2-enoylpyridines catalyzed by chiral bifunctional amine-squaramides

The diastereo- and enantioselective direct vinylogous Michael addition reaction of γ-substituted butenolides to 2-enoylpyridines has been achieved. A range of γ,γ-disubstituted butenolide derivatives, bearing two consecutive tri- and tetrasubstituted stereogenic centers, were readily obtained in good yields with excellent stereoselectivities (up to >99:1 dr and >99% ee).