61893-09-2

Usage

Uses

Used in Medical Applications:
1-Ethylimidazolidine-2,4-dione is used as a chelating agent for treating conditions related to excess metal accumulation in the body, such as heavy metal poisoning.
Used in Pharmaceutical Production:
1-Ethylimidazolidine-2,4-dione is used as a raw material in the production of pharmaceuticals, contributing to the development of various medications.
Used in Personal Care Products:
1-Ethylimidazolidine-2,4-dione is used as an ingredient in personal care products, where its chelating properties can be beneficial.
Used in Detergent and Cleaning Agent Manufacturing:
1-Ethylimidazolidine-2,4-dione is used as a chelating agent in the manufacturing of detergents and cleaning agents, enhancing their effectiveness in removing dirt and stains.
Used in Chemical and Industrial Processes:
1-Ethylimidazolidine-2,4-dione is used in various chemical and industrial processes due to its chelating properties and its ability to bind to metal ions, making it an important compound in these fields.

InChI:InChI=1/C5H8N2O2/c1-2-7-3-4(8)6-5(7)9/h2-3H2,1H3,(H,6,8,9)

Upstream product

• 627-01-0 N-ethylglycine 
• 57-13-6 urea 
• 590-28-3 potassium cyanate 
• 4791-21-3 (2-chloroacetyl)urea 
• 75-04-7 ethylamine 
• 79-19-6 thiosemicarbazide 
• 177781-53-2 1-ethyl-4,5-dihydroxyimidazolidin-2-one 
• 131543-46-9 Glyoxal 
• 625-52-5 N-Ethylurea 

Relevant academic research and scientific papers

Photocatalytic Intramolecular C-H Amination Using N-Oxyureas as Nitrene Precursors

Nitrenes are remarkable high-energy chemical species that enable direct C-N bond formation, typically via controlled reactions of metal-stabilized nitrenes. Here, in contrast, the combined use of photocatalysis with careful engineering of the precursor enabled C-H amination forming imidazolidinones and related nitrogen heterocycles from readily accessible hydroxylamine precursors. Preliminary mechanistic results are consistent with the formation of free carbamoyl triplet nitrenes as reactive intermediates.

11,13-MODIFIED SAXITOXINS FOR THE TREATMENT OF PAIN

Provided herein are compounds, pharmaceutical compositions comprising the compounds, methods of preparing the compounds, and methods of using the compounds and compositions in treating conditions associated with voltage-gated sodium channel function where the compounds are 11,13-modified saxitoxins according to Formula (I): where R4, R4a, R7, R7a, and X2 are as described herein.

α-Ureidoalkylation of thiosemicarbazide and aminoguanidine

Optimum conditions for the targeted synthesis of 5,7-dialkyl-3- thioxoperhydroimid-azo[4,5-e][1,2,4]triazin-6-ones, 4,5-bis(3- thiosemicarbazido(guanidinoamino))imidazolidin-2-ones, and 1,3-dialkyl-4- (guanidinoimino)imidazolidin-2-ones by α-ureidoalkylation of thiosemicarbazide or aminoguanidine were found. A novel conglomerate in the series of imidazolidin-2-one derivatives was detected: 4,5-bis(guanidinoamino)- 1,3-dimethylimid-azolidin-2-one dihydrochloride dihydrate. Springer Science+Business Media, Inc. 2006.

Synthesis of new chiral mono-, di-, tri-, and tetraalkylglycolurils

Two general procedures were developed for the synthesis of chiral N-mono-, N, N′-di-, N, N′ N″-tri-, and N, N′, N″, N′″-tetraalkylglycolurils based on the reactions of 4,5-dihydroxy-imidazolidin-2-ones or glyoxal with one or two moles of alkylureas, respectively, by acid catalysis. The reactions of N-monoalkyl- and N, N′-dialkylureas with glyoxal proceed regioselectively. The mechanism of these reactions was suggested and partly confirmed by quantum-chemical calculations and experimental data. The enantiomeric separation of some chiral glycolurils by chiral-phase HPLC was carried out for the first time.