619323-39-6

Basic information

• Product Name: 2-(3-bromophenyl)pent-4-enoic acid
• Synonyms: 2-(3-bromophenyl)pent-4-enoic acid
• CAS NO: 619323-39-6
• Molecular Weight: 255.111
• Mol File: 619323-39-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3-bromophenyl)pent-4-enoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-bromophenyl)pent-4-enoic acid(619323-39-6)
• EPA Substance Registry System: 2-(3-bromophenyl)pent-4-enoic acid(619323-39-6)

Safety Data

• Hazardous Substances Data: 619323-39-6(Hazardous Substances Data)

Usage

Derivative of pent-4-enoic acid

2-(3-bromophenyl)pent-4-enoic acid is derived from pent-4-enoic acid by attaching a bromophenyl group to its structure.

Bromophenyl group attachment

The bromophenyl group is attached at the 3-position of the pentene chain, which influences the compound's properties and reactivity.

Use in organic synthesis

2-(3-bromophenyl)pent-4-enoic acid is used as a building block in organic synthesis for the creation of various biologically active molecules.

Application in pharmaceutical research

The compound is valuable in pharmaceutical research for the synthesis of drugs and other complex organic compounds.

Unique structure and properties

The structure and properties of 2-(3-bromophenyl)pent-4-enoic acid make it a sought-after intermediate for creating a wide range of biologically active molecules.

Upstream product

• 1878-67-7 3-Bromophenylacetic acid 
• 106-95-6 allyl bromide 
• 331-25-9 (3-fluorophenyl)acetic acid 
• 64123-77-9 methyl (3-fluorophenyl)acetate 
• 150529-73-0 methyl 2-(3-bromophenyl)acetatee 
• 619323-22-7 methyl 2-(3-bromophenyl)pent-4-enoate 
• 619323-20-5 methyl 2-(3-fluorophenyl)pent-4-enoate 

Downstream Products

• 619323-22-7 methyl 2-(3-bromophenyl)pent-4-enoate 
• 301854-30-8 3-(3-bromophenyl)-5-methyltetrahydrofuran-2-one 

Relevant articles and documents

GAMMA-AMINOAMIDE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

The present invention is directed to compounds of the formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R11, R12, W, X, and n are defined herein, which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2.

3-Phenyl-5-methyl-2H,5H-furan-2-ones: Tuning antifungal activity by varying substituents on the phenyl ring

A series of racemic 3-phenyl-5-methyl-2H,5H-furan-2-ones related to a natural product, (-)incrustoporine, was synthesized, and their antifungal activity evaluated. The key structural feature, furanone ring, was closed via H2SO4-mediated cyclization of 2-phenylpent-4-enoic acids. The compounds displayed antifungal activity, especially against filamentous fungi. Expressed as the minimum inhibition concentration (MIC) in μmol/L, the activity of the most promising derivative against Absidia corymbifera matched that of ketoconazole (31.25 μmol/L). In terms of μg/mL, the substance was more active (7.6 μg/mL) than this standard antifungal drug (16.6 μg/mL). (C) 2000 Elsevier Science Ltd. All rights reserved.