61938-65-6

Basic information

• Product Name: Pyrrolo[2,1-b]quinazolin-9(1H)-one
• Synonyms: Pyrrolo[2,1-b]quinazolin-9(1H)-one;7-Bromo-2,3-dihydro-1H-pyrrolo[2,1-b]quinazolin-9-one;7-BROMO-2,3-DIHYDROPYRROLO[2,1-B]QUINAZOLIN-9(1H)-ONE
• CAS NO: 61938-65-6
• Molecular Formula: C₁₁H₉BrN₂O
• Molecular Weight: 184.19402
• Mol File: 61938-65-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Pyrrolo[2,1-b]quinazolin-9(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolo[2,1-b]quinazolin-9(1H)-one(61938-65-6)
• EPA Substance Registry System: Pyrrolo[2,1-b]quinazolin-9(1H)-one(61938-65-6)

Safety Data

• Hazardous Substances Data: 61938-65-6(Hazardous Substances Data)

Upstream product

• 5794-88-7 5-Bromo-2-aminobenzoic acid 
• 56-12-2 4-amino-n-butyric acid 
• 118-92-3 anthranilic acid 
• 495-59-0 deoxypeganine 
• 616-45-5 2-pyrrolidinon 
• 61939-05-7 2,3-trimethylene-3,4-dihydroquinazoline hydrochloride 

Downstream Products

• 133566-55-9 4-Benzoyl-7-bromo-2,3,3a,4-tetrahydro-1H-pyrrolo[2,1-b]quinazolin-9-one 

Relevant articles and documents

Synthesis of hybrid molecules containing fragments of sesquiterpene lactones and plant alkaloids

The Pd-catalyzed arylation of isoalantolactone by deoxyvasicinone and lappaconitine halides occurred with formation mainly of cross-coupling products with the (E)-configuration of the double bond. Another three compounds were isolated from the reaction of

Synthesis of {2,3-dihydro-7-halopyrrolo-[(2,1-b)]-quinazolin-9-(1h)-one and 2,3-dihydro-5,7-dihalopyrrolo-[(2,1-b)]-quinazolin-9-(1h)-one}: New analogs of deoxyvasicinone

A series of novel halogen-substituted deoxyvasicinone f2,3-dihydro-7- halopyrrolo-[(2,1-b)]-quinazolin-9-(1H)-one and 2,3-dihydro-5,7-dihalopyrrolo- [(2,1-b)]-quinazolin-9-(1H)-oneg derivatives was synthesized by condensation of halogenated anthranilic acids (2, 3, 4, 5) with 4-aminobutyric acid (6) in refluxing m-xylene over phosphorus pentoxide for 3 h to give the desired compounds (7a-7d). Taylor & Francis Group, LLC.

One-pot synthesis of simple alkaloids: 2,3-Polymethylene-4(3H)- quinazolinones, luotonin A, tryptanthrin, and rutaecarpine

One-pot synthesis of various 2,3-polymethylene-4(3H)-quinazolinones from anthranilic acid, corresponding lactam and SOCl2 is described, which can be applicable to the synthesis of simple 4(3H)-quinazolinone-derived alkaloids, such as luotonin A, tryptanthrin, and rutaecarpine.