61986-78-5Relevant academic research and scientific papers
Transition-Metal-Free Arylation and Alkylation of Diarylmethyl p-Tolyl Sulfones with Zinc Reagents
Miao, Maozhong,Yin, Wenguang,Wang, Lei,Chen, Zhengkai,Xu, Jianfeng,Ren, Hongjun
, p. 10602 - 10612 (2018/09/06)
The transition-metal-free synthesis of unsymmetrical and highly functionalized triarylmethanes through arylation of the situ generated o-QMs from diarylmethyl p-tolyl sulfones with aryl zinc reagents is described. Alkyl zinc reagents are also well tolerated in this reaction. Additionally, the straightforward synthesis of the analogue of the antituberculosis agent A and the key precursor of the anti-breast-cancer agent B are achieved by this strategy.
Number and Structure of Solvolysis Intermediates. Part 2. A Novel Example of the Common Ion Rate Depression Arising at the Stage of the Second Ion Pair Intermediate in the SN1 Solvolysis
Kinoshita, Tomomi,Shibayama, Koichi,Itoh, Masaaki,Takeuchi, Ken'ichi
, p. 1727 - 1731 (2007/10/02)
The solvolysis of 2,2-dimethyl-1-(p-methoxyphenyl)propyl p-nitrobenzoate in phenol provides a novel example of the common ion salt effect (rate depression) which arises at the stage of the second ion pair intermediate (Int-2; the rear-side shilded ion pair intermediate), not the dissociated (free) carbocation intermediate as generally supposed so far.This example demonstrates that "the common ion rate depression" could not give evidence for the intermediacy of the dissociated carbocation intermediate in the SN1 solvolysis, but an indicator for the stability of solvolysis intermediates including the ion pair intermediate.
