61995-18-4

Basic information

• Product Name: 1-Piperidine carboxylic acid-3-oxo-Methyl ester
• Synonyms: 1-Piperidine carboxylic acid-3-oxo-Methyl ester;Methyl3-oxopiperidine-1-carboxylate
• CAS NO: 61995-18-4
• Molecular Formula: C₇H₁₁NO₃
• Molecular Weight: 157.16714
• Mol File: 61995-18-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-Piperidine carboxylic acid-3-oxo-Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperidine carboxylic acid-3-oxo-Methyl ester(61995-18-4)
• EPA Substance Registry System: 1-Piperidine carboxylic acid-3-oxo-Methyl ester(61995-18-4)

Safety Data

• Hazardous Substances Data: 61995-18-4(Hazardous Substances Data)

Usage

General Description

1-Piperidine carboxylic acid-3-oxo-Methyl ester, also known as 3-Piperidone, is a chemical compound with the molecular formula C7H11NO2. It is commonly used as an intermediate in chemical synthesis and pharmaceutical research. 1-Piperidine carboxylic acid-3-oxo-Methyl ester is a white crystalline solid with a molecular weight of 141.17 g/mol. It is primarily used in the synthesis of various drugs and agrochemicals. Additionally, 1-Piperidine carboxylic acid-3-oxo-Methyl ester has potential applications in the development of new materials and as a building block in organic synthesis. It is important to handle this chemical with care, as it may be hazardous if not used properly.

Upstream product

• 56475-87-7 3,4-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 40114-49-6 1-benzyl-3-piperidone 
• 79-22-1 methyl chloroformate 
• 50606-58-1 N-benzyl-3-piperidinone hydrochloride 
• 80613-04-3 3-hydroxypiperidine-1-carboxylic acid methyl ester 

Downstream Products

• 1000893-93-5 C₃₆H₄₀F₆N₄O₅ 
• 1000894-33-6 C₁₉H₂₂F₃NO₅ 
• 1132910-38-3 methyl 3-(2-(tert-butoxycarbonylamino)phenyl)-3-hydroxypiperidine-1-carboxylate 
• 5451-09-2 5-aminolevulinic acid hydrochloride 
• 866823-00-9 2-(2-bromo-5-methoxybenzyl)-3-hydroxy-3,5-bis(3-methoxyphenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 866822-97-1 2-(2-bromo-5-methoxybenzyl)-3-hydroxy-3-(3-methoxyphenyl)-piperidine-1-carboxylic acid methyl ester 
• 866822-99-3 2-(2-bromo-5-methoxybenzyl)-5-(3-methoxyphenyl)-3-oxo-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 866822-95-9 2-(2-bromo-5-methoxybenzyl)-3-hydroxy-3-(3-methoxyphenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 866822-90-4 3-hydroxy-2-(3-methoxybenzyl)-3-(3-methoxyphenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 866822-93-7 2-(2-bromo-5-methoxybenzyl)-3-oxopiperidine-1-carboxylic acid methyl ester 
• 866822-94-8 2-(2-bromo-5-methoxybenzyl)-3-oxo-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 866822-89-1 2-(3-methoxybenzyl)-3-oxo-3,6-dihydro-2H-pyridine-1-carboxylic acid methyl ester 
• 80613-04-3 3-hydroxypiperidine-1-carboxylic acid methyl ester 

Relevant articles and documents

Pivotal role of an aliphatic side chain in the development of an HDM2 inhibitor

Introduction of an aliphatic side chain to a key position of a novel piperidine-based HDM2 inhibitor scaffold resulted in significant potency gains, enabling further series progression.

Substituted Piperidines that Increase P53 Activity and the Uses Thereof

In its many embodiments, the present invention discloses novel compounds, as inhibitors of HDM2 protein, methods for preparing such compounds, pharmaceutical compositions including one or more such compounds, methods of treatment, prevention, inhibition, of one or more diseases associated with the HDM2 protein or P53 using such compounds or pharmaceutical compositions.

A convenient method for introducing oxo group into the β-position of cyclic amines and its application to synthesis of δ-aminolevulinic acid

Oxo group could be introduced into the β-position of N-methoxycarbonylated cyclic amines by utilizing electrochemical oxidation and/or m-chloroperbenzoic acid oxidation, and this method was applied to the preparation of δ-aminolevulinic acid, an intermediate of chlorophyll biosynthesis.