62024-69-5

Basic information

• Product Name: 1,2-Ethanediamine, N-(2,4-dinitrophenyl)-, monohydrochloride
• Synonyms: N-(2,4-dinitrophenyl)ethane-1,2-diamine hydrochloride;N-(2,4-dinitro-phenyl)-ethylenediamine, hydrochloride;N-(2,4-Dinitro-phenyl)-aethylendiamin, Hydrochlorid;N1-(2,4-dinitrophenyl)ethane-1,2-diamine hydrochloride;N-(2,4-dinitrophenyl)ethylenediamine hydrochloride
• CAS NO: 62024-69-5
• Molecular Formula: C8H10N4O4.ClH
• Molecular Weight: 262.65000
• Mol File: 62024-69-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,2-Ethanediamine, N-(2,4-dinitrophenyl)-, monohydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Ethanediamine, N-(2,4-dinitrophenyl)-, monohydrochloride(62024-69-5)
• EPA Substance Registry System: 1,2-Ethanediamine, N-(2,4-dinitrophenyl)-, monohydrochloride(62024-69-5)

Safety Data

• Hazardous Substances Data: 62024-69-5(Hazardous Substances Data)

Usage

General Description

1,2-Ethanediamine, N-(2,4-dinitrophenyl)-, monohydrochloride is a chemical compound used in the synthesis of pharmaceuticals, dyes, and pesticides. It is a derivative of ethylenediamine, which is used as a chelating agent in various industrial processes. The monohydrochloride form of this compound makes it more water-soluble and suitable for use in aqueous solutions. It is also known for its ability to form complexes with metal ions, making it useful in analytical chemistry for metal ion detection and separation. Additionally, it has been investigated for its potential use in the treatment of various medical conditions, including cancer. However, it is important to handle this compound with caution, as it is toxic and can cause irritation to the skin, eyes, and respiratory system.

Upstream product

• 107-15-3 ethylenediamine 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 333-18-6 1,2-diaminoethane dihydrochloride 
• 99-65-0 meta-dinitrobenzene 

Downstream Products

• 923001-75-6 C₁₉H₂₇N₇O₉ 
• 873223-13-3 C₁₇H₂₄N₆O₈ 
• 154036-02-9 C₃₄H₄₀N₆O₉ 
• 28767-75-1 N¹-(2,4-dinitrophenyl)ethane-1,2-diamine 
• 154036-08-5 tert-butyl (S)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-((2-((2,4-dinitrophenyl)amino)ethyl)amino)-5-oxopentanoate 

Relevant articles and documents

In silico design, synthesis, and assays of specific substrates for proteinase 3: Influence of fluorogenic and charged groups

Neutrophil serine proteases are specific regulators of the immune response, and proteinase 3 is a major target antigen in antineutrophil cytoplasmic antibody-associated vasculitis. FRET peptides containing 2-aminobenzoic acid (Abz) and N-(2,4-dinitrophenyl)ethylenediamine (EDDnp) as fluorophore and quencher groups, respectively, have been widely used to probe proteases specificity. Using in silico design followed by enzymatic assays, we show that Abz and EDDnp significantly contribute to substrate hydrolysis by PR3. We also propose a new substrate specific for PR3.

Synthesis of (alkylamino)nitroarenes by oxidative alkylamination of nitroarenes

The viability of the oxidative alkylamination process for the derivatization of electron-deficient carboaromatics has been investigated. 1,3-Dinitrobenzene, 1-nitronaphthalene, and 1,5- and 1,8-dinitronaphthalenes have shown to react with a wide range of alkylamines in the presence of an oxidant (KMnO4, AgMnO4, AgPy2MnO4) to give access to the corre sponding N-alkyl-nitroarenamines in moderate to good yields. Nitroarenes are more reactive than azines towards alkylamines.