62033-58-3

Basic information

• Product Name: Piperidine, 3-(3,4-dimethoxyphenyl)-
• CAS NO: 62033-58-3
• Molecular Formula: C13H19NO2
• Molecular Weight: 221.299
• Mol File: 62033-58-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Piperidine, 3-(3,4-dimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 3-(3,4-dimethoxyphenyl)-(62033-58-3)
• EPA Substance Registry System: Piperidine, 3-(3,4-dimethoxyphenyl)-(62033-58-3)

Safety Data

• Hazardous Substances Data: 62033-58-3(Hazardous Substances Data)

Upstream product

• 89980-69-8 3,4-dimethoxyphenylmagnesium bromide 
• 626-55-1 3-Bromopyridine 
• 79445-45-7 3-(3,4-Dimethoxyphenyl)pyridine 

Downstream Products

• 62033-61-8 3-(3,4-dimethoxyphenyl)-1-propylpiperidine 
• 62033-63-0 N-(β-phenylethyl)-3-(3',4'-dimethoxyphenyl)-piperidine 
• 62033-60-7 N-acetyl-3-(3',4'-dimethoxyphenyl)-piperidine 
• 62033-50-5 3-(3,4-dihydroxyphenyl)-N-n-propylpiperidine 
• 61832-52-8 3-(3',4'-dihydroxyphenyl)-piperidine hydrobromide 
• 62033-57-2 3-(3,4-dimethoxy-phenyl)-1-methyl-piperidine; hydrochloride 

Relevant articles and documents

3-Phenylpiperidines. Central Dopamine-Autoreceptor Stimulating Activity

Thirty compounds related to the selective dopamine-autoreceptor agonist 3-(3-hydroxyphenyl)-N-n-propylpiperidine have been synthesized and tested for central dopamine-autoreceptor stimulating activity.The 3-(3-hydroxyphenyl)piperidine moiety seems indispensable for high potency and selectivity.Introduction of an additional hydroxyl group into the 4-position of the aromatic ring gives a compound with dopaminergic activity but lacking selectivity for autoreceptors. 3-(3-Hydroxyphenyl)-N-n-propylpyrrolidine, 3-(3-hydroxy)-N-n-propylperhydroazepine, and 3-(3-hydroxyphenyl)quinuclidine were all inactive.The most potent compounds were the N-isopropyl-, N-n-butyl-, N-n-pentyl-, and N-phenethyl-substituted 3-(3-hydroxyphenyl)piperidine derivatives.None of the compounds investigated seemed to have central noradrenaline- or serotonin-receptor stimulating activity.

Studies on benzoisogranatanine derivatives. II. Synthesis of 1-phenethyl-2,4-propano-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolines.

-