62049-82-5

Basic information

• Product Name: Benzene, 1-nitro-2,4-bis(phenylthio)-
• Synonyms: Benzene,1-nitro-2,4-bis(phenylthio)
• CAS NO: 62049-82-5
• Molecular Formula: C18H13NO2S2
• Molecular Weight: 339.43100
• Mol File: 62049-82-5.mol

Chemical Properties

• CAS DataBase Reference: Benzene, 1-nitro-2,4-bis(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-nitro-2,4-bis(phenylthio)-(62049-82-5)
• EPA Substance Registry System: Benzene, 1-nitro-2,4-bis(phenylthio)-(62049-82-5)

Safety Data

• Hazardous Substances Data: 62049-82-5(Hazardous Substances Data)

Upstream product

• 123-91-1 1,4-dioxane 
• 64-17-5 ethanol 
• 860241-51-6 4-benzenesulfonyl-1-nitro-2-phenylsulfanyl-benzene 
• 930-69-8 sodium thiophenolate 
• 672295-04-4 (5-chloro-2-nitro-phenyl)-phenyl sulfone 
• 610-40-2 3,4-dinitro-chlorobenzene 
• 26815-49-6 1-amino-3-phenylsulfonylbenzene 
• 24509-46-4 5-benzenesulfonyl-2-nitro-aniline 
• 856358-11-7 acetic acid-(3-benzenesulfonyl-anilide) 
• 857620-70-3 acetic acid-(5-benzenesulfonyl-2-nitro-anilide) 
• 854636-42-3 toluene-4-sulfonic acid-(5-benzenesulfonyl-2-nitro-anilide) 
• 611-06-3 2,4-dichloronitrobenzene 
• 4551-15-9 phenylthiotrimethylsilane 
• 446-35-5 2,4-Difluoronitrobenzene 

Downstream Products

• 860518-87-2 2,4-bis-benzenesulfonyl-1-nitro-benzene 
• 70415-98-4 1,2,4-tris-benzenesulfonyl-benzene 
• 860241-51-6 4-benzenesulfonyl-1-nitro-2-phenylsulfanyl-benzene 
• 857955-03-4 2,4-bis-benzenesulfonyl-1-phenylsulfanyl-benzene 

Relevant articles and documents

Microwave-promoted TBAF-catalyzed SNAr reaction of aryl fluorides and ArSTMS: An efficient synthesis of unsymmetrical diaryl thioethers

Microwave irradiation was found to promote tetrabutylammonium fluoride catalyzed nucleophilic aromatic substitution of aryl fluorides and arylthiotrimethylsilanes, affording high yields of unsymmetrical diaryl thioethers efficiently under mild, transition-metal- and base-free conditions. Microwave showed unusual improvement on the reaction in not only the conditions and reaction rate, but also in selectivity and substrate scope. Georg Thieme Verlag Stuttgart - New York.

TBAF-catalysed facile synthesis of unsymmetrical diaryl thioethers via mild SNAr reactions

By using tetrabutylammonium fluoride as the catalyst, the synthesis of unsymmetrical diaryl thioethers could be easily achieved in high yields via a mild nucleopilic aromatic substitution reaction of aryl fluorides and phenylthiotrimethylsilane.

Ortho-selectivity in SNAr substitutions of 2,4-dihaloaromatic compounds. Reactions with anionic nucleophiles

The nucleophilic addition of organic anions to aromatic compounds with halogens positioned both ortho and para to activating groups was studied in a variety of solvents. Substrates showed strong preferences for ortho substitution in most cases. Evidence is presented for activating group-dependent coordination, which contributes to very high ortho-selectivity in nonpolar solvents. This also drives the overall reaction rate in these solvents, and is of close to the same magnitude of rate increase derived from polar solvents. para-Products are maximized by using crown ethers in protic solvents. Solvent effects overall are very different from corresponding reactions with amine nucleophiles due primarily to the different charges present in the transition states, and to solvation of the nucleophile.

Certain azaphenoxathiin compounds

A pharmacological composition useful as potential central nervous system depressants and weight control agents in animals and humans comprising a substituted aromatic Tricyclic and Pentacyclic sulfide wherein the aromatic is phenyl, pyridyl, pyrazidyl, pyrimidyl, and isosteric substitutions including elements in Group VI-a of the Periodic Table.