62075-55-2

Basic information

• Product Name: 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid
• Synonyms: 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid;1,3-Dioxolane-4-carboxylic acid, 2,2-dimethyl-;2,2-Dimethyl-1,3-dioxolane-4-carboxylic
• CAS NO: 62075-55-2
• Molecular Formula: C6H10O4
• Molecular Weight: 146.1412
• Product Categories: Heterocycles series
• Mol File: 62075-55-2.mol
• Article Data: 41

Chemical Properties

• Boiling Point: 244.151 °C at 760 mmHg
• Flash Point: 101.605 °C
• Appearance: /
• Density: 1.203 g/cm³
• Vapor Pressure: 0.01mmHg at 25°C
• Refractive Index: 1.447
• CAS DataBase Reference: 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid(62075-55-2)
• EPA Substance Registry System: 2,2-Dimethyl-1,3-Dioxolane-4-Carboxylic Acid(62075-55-2)

Safety Data

• Hazardous Substances Data: 62075-55-2(Hazardous Substances Data)

Usage

General Description

2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid is a chemical compound with the molecular formula C7H12O4. It is a carboxylic acid with a dioxolane ring and two methyl substituents. 2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid is often used in pharmaceutical research and drug development due to its potential biological activities. It has been studied for its antimicrobial and antifungal properties and has also been investigated for its potential use in the treatment of various diseases. Additionally, 2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid has been utilized in organic synthesis as a building block for the preparation of more complex molecules.

InChI:InChI=1/C6H10O4/c1-6(2)9-3-4(10-6)5(7)8/h4H,3H2,1-2H3,(H,7,8)

Upstream product

• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 52373-72-5 methyl (R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 14131-84-1 2,3:5,6-di-O-isopropylidene-α-D-mannofuranose 
• 7306-64-1 2,3,5,6-di-O-isopropylidene-D-mannono-1,4-lactone 
• 60456-21-5 methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 14347-78-5 1,2-O-isopropylidene-D-glycerol 
• 108865-84-5 methyl 2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 134036-81-0 (4S,5S)-5-[(R)-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-hydroxy-methyl]-2,2-dimethyl-[1,3]dioxolane-4-carboxylic acid anion 
• 55032-17-2 (4R)-4-benzyloxycarbonyl-2,2-dimethyl-1,3-dioxolane 
• 22323-82-6 (S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 15186-48-8 2,3-isopropylidene-glyceraldehyde 
• 14028-61-6 potassium (R)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 22323-80-4 (4S)-2,2-dimethyl-[1,3]dioxolane-4-carbaldehyde 

Downstream Products

• 148065-34-3 (R)-2,2-dimethyl-1,3-dioxolane-4-carboxamide 
• 99566-52-6 (S)-(2,2-dimethyl-1,3-dioxolan-4-yl)ethanone 
• 60456-21-5 methyl (4S)-2,2-dimethyl-1,3-dioxolane-4-carboxylate 
• 90493-96-2 2,2-dimethyl-1,3-dioxolane-4-carboxylic acid chloride 

Relevant articles and documents

ARYLMETHYLENE HETEROCYCLIC COMPOUNDS AS KV1.3 POTASSIUM SHAKER CHANNEL BLOCKERS

A compound of Formula (I) or a pharmaceutically acceptable salt thereof is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.

THERAPEUTIC METHODS

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Electrochemical Oxidation of Alcohols and Aldehydes to Carboxylic Acids Catalyzed by 4-Acetamido-TEMPO: An Alternative to "anelli" and "pinnick" Oxidations

An electrocatalytic method has been developed to oxidize primary alcohols and aldehydes to the corresponding carboxylic acids using 4-acetamido-2,2,6,6-tetramethylpiperidin-1-oxyl (ACT) as a mediator. The method successfully converts benzylic, aliphatic, heterocyclic, and other heteroatom-containing substrates to the corresponding carboxylic acids in aqueous solution at room temperature. The mild conditions enable retention of stereochemistry adjacent to the site of oxidation, as demonstrated in a 40 g-scale synthesis of a precursor to levetiracetam, a medication used to treat epilepsy.