62089-28-5Relevant academic research and scientific papers
Ultrasound assisted synthesis of 1,5-disubstituted pyrazole using Cu(I) catalyst
Pise, Ashok S.,Burungale, Arvind S.,Devkate, Santosh S.
, p. 575 - 579 (2020/02/06)
A new efficient and convenient approach towards the synthesis of pyrazole is described. The α,β-unsaturated cyanoesters were obtained from substituted benzaldehyde and ethyl cyanoacetate by reported methods. 1,5-Disubstituted pyrazoles were synthesized fr
Enaminones as building blocks: Synthesis of novel substituted pyrazoles as possible antioxidants
Shetty, Shobhitha,Asma,Kalluraya, Balakrishna
, p. 501 - 506 (2017/01/18)
An efficient synthesis of some new novel series of 1,5-disubstituted pyrazole derivatives have been achieved by reacting different enaminones with various hydrazines. The structures of the newly synthesized compounds have been elucidated from elemental an
BENZISOXAZOLE MODULATORS OF NEUROGENESIS
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Page/Page column 20, (2014/02/16)
The present invention relates to compounds of general formula (I) wherein Ar1/Ar2 are phenyl or a 5 or 6-membered heteroaryl; R1/R2 is hydrogen, halogen, lower alkyl, CF3 or lower alkoxy; n,m are 1 or 2; or to a pharmaceutically acceptable acid addition salt, to a racemic mixture or to its corresponding enantiomer and/or optical isomers thereof, with the exception of the compound 2,1-benzisoxazole,3-(4-chlorophenyl)-5-(1-phenyl-1H-pyrazol-5-yl)-. The compounds may be used for the treatment of schizophrenia, obsessive-compulsive personality disorder, major depression, bipolar disorders, anxiety disorders, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal cord injury, post-traumatic stress disorder, panic disorder, Parkinson's disease, dementia, Alzheimer's disease, mild cognitive impairment, chemotherapy-induced cognitive dysfunction, Down syndrome, autism spectrum disorders, hearing loss, tinnitus, spinocerebellar ataxia, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of neuro-active drugs, such as alcohol, opiates, methamphetamine, phencyclidine and cocaine.
New Synthesis of Pyrazole and Isoxazole Derivatives
Molina, P.,Fresneda, P. M.
, p. 461 - 464 (2007/10/02)
A convenient synthesis of 5-aryl-1-phenylpyrazoles and 5-arylisoxazoles, from readily available ketimine 1 dimethylformamide dimethylacetal and phenylhydrazine or hydroxylamine, is described.
