6209-23-0Relevant academic research and scientific papers
Synthesis, characterization and biological evaluation of some newer carbazole derivatives
Sharma, Divyanshu,Kumar, Nitin,Pathak, Devender
, p. 125 - 132 (2014)
A series of novel 5-[(9H-carbazol-9-yl)methyl]-N-[(substituted phenyl)( piperazin-1-yl)methyl]-1,3,4-oxadiazol-2-amines (4a-o) derivatives was synthesized by starting with carbazole, which on reaction with ethyl chloroacetate yielded ethyl 2-(9H-carbazole
Metal ion clip: Fine-tuning aromatic stacking interactions in the multistep formation of carbazole-bridged zinc(ii) complexes
Imai, Yuki,Kawai, Tsuyoshi,Yuasa, Junpei
, p. 10103 - 10106 (2015)
A carbazole-based triple bridging ligand (LH) consisting of two imidazole moieties at 3,6 positions with a diketone unit at the carbazole nitrogen forms carbazole-bridged zinc(ii) complexes with structures of [(L-)4(Zn2+)
OFF-ON-OFF Dual Emission at Visible and UV Wavelengths from Carbazole Functionalized β-Diketonate Europium(III) Complex
Imai, Yuki,Kawai, Tsuyoshi,Yuasa, Junpei
, p. 4131 - 4138 (2016)
This work demonstrates dual emission "OFF-ON-OFF" switching at visible and UV wavelengths of a carbazole functionalized β-diketone (LH) by a simple change of a europium(III) ion (Eu3+) concentration in the submicromolar concentration range. In
Carbazole oxadiazole conjugates, and preparation method and application thereof
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Paragraph 0042-0044, (2019/10/23)
The invention relates to carbazole oxadiazole conjugates, and a preparation method and an application thereof, and belongs to the technical field of chemical synthesis. The carbazole oxadiazole conjugates are represented by general formula I. The above co
Carbazole-isatin type compound and preparation method and application thereof
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Paragraph 0010, (2016/10/08)
The invention discloses a carbazole-isatin type compound and a preparation method and application thereof.The compound is of a structure as shown in a formula (I), and the preparation method comprises the steps of using carbazole and ethyl bromoacetate as raw materials to obtain 2-(9H-carbazole-9-yl) ethyl acetate, then performing hydrazinolysis reaction to obtain 2-(9H-carbazole-9-yl) acethydrazide, and finally performing reaction with various types of substitutive isatin to obtain a target compound.The compound can serve as a raw material for anti-tumor drugs, the raw materials for the preparation method are simple and easy to obtain, and operation is convenient.
Substituted Carbazoles-A New Class of Anthelmintic Agent
Rennison, David,Gueret, Stephanie M.,Laita, Olivia,Bland, Ross J.,Sutherland, Ian A.,Boddy, Ian K.,Brimble, Margaret A.
, p. 1268 - 1276 (2016/11/25)
A series of novel carbazoles were synthesized based on structural modifications to lead carbazole 1 (EC100≤2.5M against Haemonchus contortus in vitro), which was revealed in a small molecule screening program as a potentially promising platform for the development of new anthelmintic drugs. Subsequently, analogues 19, 21, 41, 42 (EC100≤ 1.25M, all), and 39 (EC100≤0.625M) were demonstrated to exhibit enhanced in vitro anthelmintic activity over the lead structure, with compound 39 also being shown to be active in vivo against Heligmosomoides polygyrus.
Unveiling photodeactivation pathways for a new iridium(III) cyclometalated complex
Escudero, Daniel,Heuser, Eike,Meier, Robert J.,Schaeferling, Michael,Thiel, Walter,Holder, Elisabeth
, p. 15639 - 15644 (2013/11/19)
We report the synthesis and characterization of a neutral heteroleptic IrIII complex bearing 6-fluoro-2-phenylbenzo[d]thiazole as cyclometalating ligand and (Z)-6-(9H-carbazol-9-yl)-5-hydroxy-2,2-dimethylhex-4- en-3-one as ancillary ligand. The
Solid-liquid phase alkylation of n-heterocycles: Microwave-assisted synthesis as an environmentally friendly alternative
Milen, Matyas,Gruen, Alajos,Balint, Erika,Dancso, Andras,Keglevich, Gyoergy
experimental part, p. 2291 - 2301 (2010/09/17)
The solid-liquid phase alkylation of a variety of five-membered N-heterocycles (carbazole, imidazole, benzimidazole, and indole-3-carbaldehyde) was carried out under different conditions. The use of alkali carbonate in dimethylformamide or in MeCN (in the latter case, in the presence of a phase-transfer catalyst) is a suitable method to prepare the corresponding N-alkylated products in an efficient way. In most cases, the solventless, microwave-assisted reaction is an environmentally friendly alternative to traditional methods. Copyrigh
Synthesis and antipsychotic and anticonvulsant activity of some new substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles
Kaur, Hemlata,Kumar, Sunil,Vishwakarma, Pinki,Sharma, Monica,Saxena,Kumar, Ashok
experimental part, p. 2777 - 2783 (2010/08/22)
A novel substituted oxa/thiadiazolylazetidinonyl/thiazolidinonylcarbazoles (4a-j), (5a-j) and (6a-j) were synthesized and screened for their antipsychotic and anticonvulsant activities. It is concluded from the results compound 6j showed promising antipsy
Synthesis and characterization of six new carbazolyl porphyrins
Guo, Dong-Cai,Li, Ping-Liang,Wang, Xin,Wang, Li-Ying,Wu, Pan-Liang
experimental part, p. 3315 - 3321 (2011/01/04)
Novel 4-(N-carbazole methyl) benzoic acid and N-carbazolacetic acid are synthesized, then six new carbazolyl porphyrins are synthesized by bonding these acids to hydroxy porphyrin or amido porphyrin via acyl chloride or N,N'-dicyclohexylcarbodiimide (DCC)
