62124-30-5

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Hydroxy-ethyl)-piperidine-4-carboxylic acid amide is used as a building block for the synthesis of bioactive compounds due to its potential biological activity and the presence of a piperidine ring, which is known to contribute to a variety of pharmacological effects.
Further research and analysis are required to fully understand the compound's properties and to explore its potential applications in the pharmaceutical and other industries.

InChI:InChI=1/C8H16N2O2/c9-8(12)7-1-3-10(4-2-7)5-6-11/h7,11H,1-6H2,(H2,9,12)

Upstream product

• 39546-32-2 4-carboxamidopiperidine 
• 107-07-3 2-chloro-ethanol 
• 540-51-2 2-bromoethanol 
• 75-21-8 oxirane 

Downstream Products

• 21168-72-9 2-(4-(aminomethyl)piperidin-1-yl)ethan-1-ol 
• 26458-78-6 4-cyanoquinuclidine 
• 111041-03-3 1-(2-chloroethyl)piperidine-4-carbonitrile hydrochloride 

Relevant academic research and scientific papers

Modulators of STING (Stimulator of Interferon Genes)

Compounds of the general formula (I): or a pharmaceutically acceptable salt thereof, processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

A 1-substituted piperidine derivatives method for the preparation of

The invention discloses a preparation method of one-bit-substituted piperidine derivative, i.e., 2-(4-((ethyl-amino)methyl)piperidine-1-radical)alcohol. The preparation method adopts piperidine-4-formamide as a starting material, and obtains a target product by substitution reaction, reduction reaction and substitution reaction. The compound is an important medical intermediate.

Anti-Hiv Quinuclidine Compounds

The invention provides a therapeutic method for preventing or treating a pathological condition or symptom in a mammal, such as a human, wherein the infectivity of a pathogen such as a retrovirus toward mammalian cells is implicated and inhibition of its

Estrogen receptor ligands. Part 8: Dihydrobenzoxathiin SERAMs with heteroatom-substituted side chains

A series of benzoxathiin SERAMs with heteroatom-substituted amine side chains was prepared. Minor modifications in the side chain resulted in significant effects on biological activity, especially in uterine tissue.

LTA4 Hydrolase inhibitors

The present invention provides compounds of the formula Ar1-Q-Ar2-Y-R-Z and pharmaceutically acceptable salts thereof wherein Ar1 and Ar2 are optionally substituted aryl moieties, Z is an optionally substituted nitrogen-containing moiety which may be an acyclic, cyclic or bicyclic amine or an optionally substituted monocyclic or bicyclic nitrogen-containing heteroaromatic moiety; Q is a linking group capable of linking two aryl groups; R is an alkylene moiety; Y is a linking moiety capable of linking an aryl group to an alkylene moiety and wherein Z is bonded to R through a nitrogen atom. The compounds and pharmaceutical compositions of the present invention are useful in the treatment of inflammatory diseases which are mediated by LTB4 production, such as proriasis, ulcerative colitis, IBD and asthma.

NEW AND EFFICIENT SYNTHESES OF 4-CARBAMOYLQUINUCLIDINE

Two efficent routes starting from 4-carbamoylpiperidine or 2,2',2''-trichlorotriethylamine were developed for preparing 4-cyanoquinuclidine which was hydrolyzed to give 4-carbamoylquinuclidine, a chemical modifier of cephalosporin antibiotics.