62146-59-2Relevant articles and documents
Structure-activity relationship study on a simple cationic peptide motif for cellular delivery of antisense peptide nucleic acid
Albertshofer, Klaus,Siwkowski, Andrew M.,Wancewicz, Edward V.,Esau, Christine C.,Watanabe, Tanya,Nishihara, Kenji C.,Kinberger, Garth A.,Malik, Leila,Eldrup, Anne B.,Manoharan, Muthiah,Geary, Richard S.,Monia, Brett P.,Swayze, Eric E.,Griffey, Richard H.,Bennett, C. Frank,Maier, Martin A.
, p. 6741 - 6749 (2005)
Improving cellular uptake and biodistribution remains one of the major obstacles for a successful and broad application of peptide nucleic acids (PNAs) as antisense therapeutics. Recently, we reported the identification and functional characterization of
Degradable PEG-folate coated poly(DMAEA-co-BA)phosphazene-based polyplexes exhibit receptor-specific gene expression
Luten,van Steenbergen,Lok,de Graaff,van Nostrum,Talsma,Hennink
, p. 241 - 251 (2008/04/01)
A new cationic biodegradable polyphosphazene was developed, bearing both pendant primary and tertiary amine side groups, poly(2-dimethylaminoethylamine-co-diaminobutane)phosphazene (poly(DMAEA-co-BA)phosphazene). PEG and PEG-folate were coupled to polyple
Synthesis of Carbamate Protected Spermidine Homologues Through α,ω-Alkanediamines
Arasujo, M. Joso S. M. P.,Ragnarsson, Ulf,Trigo, M. Joaquina S. A. Amaral,Almeida, M. Lurdes S.
, p. 2143 - 2161 (2007/10/03)
The total synthesis of three triamines selectively protected in the primary amino groups (1a-c) and two triamines protected in the secondary amino function and in one of the primary amino functions (2a and 2c), based on a simple and efficient procedure, is described.
