6217-68-1

Basic information

• Product Name: P-NITROPHENYL SULFATE POTASSIUM SALT
• Synonyms: 4-NITROPHENYL SULFATE;4-NITROPHENYL SULFATE POTASSIUM SALT;SULFURIC ACID MONO(4-NITROPHENYL) ESTER POTASSIUM SALT;P-NITROPHENYL SULFATE POTASSIUM SALT;P-NITROPHENYL SULPHATE POTASSIUM SALT;POTASSIUM 4-NITROPHENYL SULFATE;POTASSIUM P-NITROPHENYL SULFATE;POTASSIUM P-NITROPHENYL SULPHATE
• CAS NO: 6217-68-1
• Molecular Formula: C₆H₄NO₆S*K
• Molecular Weight: 257.26
• EINECS: 228-288-5
• Product Categories: API intermediates;Metal Isotopes;Benzenes;Sulfur & Selenium Compounds
• Mol File: 6217-68-1.mol
• Article Data: 4

Chemical Properties

• Melting Point: 246-250 °C(lit.)
• Appearance: Pale yellow to yellow/Crystalline Powder
• Storage Temp.: −20°C
• Solubility: Water (Slightly)
• BRN: 3786392
• CAS DataBase Reference: P-NITROPHENYL SULFATE POTASSIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: P-NITROPHENYL SULFATE POTASSIUM SALT(6217-68-1)
• EPA Substance Registry System: P-NITROPHENYL SULFATE POTASSIUM SALT(6217-68-1)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• F: 8-10-21
• Hazardous Substances Data: 6217-68-1(Hazardous Substances Data)

Usage

Chemical Properties

Yellowish Cyrstalline Solid

Uses

Different sources of media describe the Uses of 6217-68-1 differently. You can refer to the following data:
1. Potassium p-Nitrophenyl Sulphate (cas# 6217-68-1) is a compound useful in organic synthesis.
2. Potassium 4-nitrophenyl sulfate has been used:as a substrate to measure arylsulfatase activity in cell-free coelomic fluidas a substrate for p-nitrophenyl glycoside-based enzyme assayto inhibit arylsulfataseas an inorganic analog of organic aryl ester sulphate

InChI:InChI=1/C6H5NO6S/c8-7(9)5-1-3-6(4-2-5)13-14(10,11)12/h1-4H,(H,10,11,12)/p-1

Upstream product

• 75-15-0 carbon disulfide 
• 100-02-7 4-nitro-phenol 
• 1080-04-2 p-nitrophenyl sulfate 

Downstream Products

• 63975-21-3 N-hydroxy-N-(4-hydroxyphenyl)acetamide 
• 100-02-7 4-nitro-phenol 

Relevant articles and documents

METHOD FOR PRODUCING P-NITROPHENYL SULFATE

PROBLEM TO BE SOLVED: To provide a method for producing a p-nitrophenyl sulfate (PNPS salt) such as potassium p-nitrophenyl sulfate (PNPS-K). SOLUTION: A p-nitrophenyl sulfate is produced by reacting p-nitrophenol (PNP) with sulfur trioxide complex in a medium having a low capacity of dissolving p-nitrophenyl sulfate such as tetrahydrofuran, and neutralizing the reaction product with tert-butoxy salt. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

34S Isotope Effect on Sulfate Ester Hydrolysis: Mechanistic Implications

In this communication, we report the first determination of 34S kinetic isotope effects (KIEs) for the hydrolysis of sulfate monoesters. The method involves the conversion of the inorganic sulfate, acquired at partial extent of reaction, to SO2, followed by isotope ratio determination by mass spectrometry. The KIEs determined for p-nitrophenyl sulfate and p-acetylphenyl sulfate are 1.0154 (±0.0002) and 1.0172 (±0.0003), respectively. These results, together with previous peripheral 18O KIE values, are inconsistent with an associative mechanism. The isotope effect method we report should also prove useful for studying the mechanism of other sulfuryl group transfers, including sulfatase and sulfotransferase reactions, as well as sulfate hydrolyses under other conditions. Copyright