62240-37-3

Usage

Uses

Used in Pharmaceutical Industry:
2-(Aminoethyl)-2-methyl-1,3-dioxolane is used as an intermediate in the synthesis of various pharmaceutical compounds for its ability to be incorporated into complex molecular structures, contributing to the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
2-(Aminoethyl)-2-methyl-1,3-dioxolane is used as a building block in the total synthesis of complex organic molecules, such as (+/-)-Methyl Homodaphniphyllate, for its ability to be modified and functionalized to create diverse chemical entities with specific properties and applications.

InChI:InChI=1/C6H13NO2/c1-6(2-3-7)8-4-5-9-6/h2-5,7H2,1H3

Upstream product

• 84764-41-0 2-(2-(2-methyl-1,3-dioxolan-2-yl)ethyl)isoindoline-1,3-dione 

Downstream Products

• 854890-30-5 [2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-carbamic acid methyl ester 
• 130179-19-0 3,3-(ethylenedioxy)-N-<<1-(phenylsulfonyl)-2-indolyl>methylene>butylamine 
• 130627-33-7 [1-(1-Benzenesulfonyl-1H-indol-3-yl)-meth-(Z)-ylidene]-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-amine 
• 113807-39-9 N-(3,4-dimethoxybenzilidene)-3,3-ethylenedioxybutylamine 
• 414909-99-2 2-(4-fluoro-2-methyl-phenyl)-piperidine-4-one 
• 130179-16-7 N-(2-hydroxyethyl)-2-<1-(phenylsulfonyl)-2-indolyl>-4-piperidone ethylene acetal 
• 142207-40-7 2-<1-(phenylsulfonyl)-2-indolyl>-4-piperidone ethylene acetal 
• 130627-35-9 N-(2-hydroxyethyl)-2-<1-(phenylsulfonyl)-3-indolyl>-4-piperidone ethylene acetal 
• 140858-28-2 2-<1-(phenylsulfonyl)-3-indolyl>-4-piperidone ethylene acetal 
• 113807-49-1 2-(3,4-dimethoxyphenyl)-1-hydroxyethyl-4-piperidone ethylene acetal 
• 113807-43-5 2-(3,4-dimethoxyphenyl)-4-piperidone ethylene acetal 
• 113807-52-6 2-(3,4-dimethoxyphenyl)-1-(methoxycarbonylmethyl)-4-piperidone ethylene acetal 
• 113807-51-5 2-(3,4-dimethoxyphenyl)-4,4-ethylenedioxy-1-piperidineacetaldehyde 
• 138489-32-4 C₃₄H₄₃NO₄Se 

Relevant academic research and scientific papers

Highly Regioselective 5-endo-tet Cyclization of 3,4-Epoxy Amines into 3-Hydroxypyrrolidines Catalyzed by La(OTf)3

Highly regioselective intramolecular aminolysis of 3,4-epoxy amines has been achieved. Key features of this reaction are (1) chemoselective activation of epoxides in the presence of unprotected aliphatic amines in the same molecules by a La(OTf)3 catalyst and (2) excellent regioselectivity for anti-Baldwin 5-endo-tet cyclization. This reaction affords 3-hydroxy-2-alkylpyrrolidines stereospecifically in high yields. DFT calculations revealed that the regioselectivity might be attributed to distortion energies of epoxy amine substrates. The use of this reaction was demonstrated by the first enantioselective synthesis of an antispasmodic agent prifinium bromide.

Synthesis method of 5-benzyl-2-tert-butyl-8-oxo-2,5-diazaspiro[3,5]nonanyl-2,5-dicarboxylic acid

The invention relates to a synthesis method of 5-benzyl-2-tert-butyl-8-oxo-2,5-diazaspiro[3,5]nonanyl-2,5-dicarboxylic acid. The technical problem of no industrial synthesis routes is mainly solved. The method comprises the following steps: carrying out a

New efficient synthesis of pyrido[2,3-c] and pyrido[3,2-c]coumarin derivatives

Various substituted pyrido[2,3-c] and pyrido[3,2-c]coumarins are efficiently prepared in three steps from 3- and 4-hydroxycoumarins, respectively and protected β-aminoketones.

Daphniphyllum Alkaloids. 10. Classical Total Synthesis of Methyl Homodaphniphyllate

Details for the first total synthesis of a Daphniphyllum alkaloid are presented.The synthesis required a total of 15 steps from the known keto acid 4 and followed the course 4 -> 10 -> 11 -> 16 -> 20 -> 24 -> 25 -> 27 -> 29 -> 36 -> 46 -> 47 -> 48 -> 49 -