62248-76-4Relevant articles and documents
Rhodium-catalyzed 1,4-addition of terminal alkynes to vinyl ketones
Lerum, Ronald V.,Chisholm, John D.
, p. 6591 - 6594 (2004)
The metal complex Rh(acac)(CO)2 in the presence of an eqimolar amount of tris(o-methoxyphenyl)phosphine provides a useful catalyst system for the 1,4-addition of alkynes to unsubstituted vinyl ketones. Best yields are obtained when the transfor
Enantioselective Nickel-Catalyzed anti-Arylmetallative Cyclizations onto Acyclic Ketones
Green, Harley,Argent, Stephen P.,Lam, Hon Wai
supporting information, p. 5897 - 5900 (2021/03/16)
Domino reactions involving nickel-catalyzed additions of (hetero)arylboronic acids to alkynes, followed by cyclization of the alkenylnickel intermediates onto tethered acyclic ketones to give chiral tertiary-alcohol-containing products in high enantioselectivities, are described. The reversible E/Z isomerization of the alkenylnickel intermediates enables overall anti-arylmetallative cyclization to occur. The ring system of the products are substructures of certain diarylindolizidine alkaloids.
Palladium-catalyzed 1,4-addition of terminal alkynes to conjugated enones
Zhou, Feng,Chen, Liang,Li, Chao-Jun
, p. 72 - 82 (2014/04/17)
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Direct conjugate addition of alkynes with α,β-unsaturated carbonyl compounds catalyzed by NCN-pincer Ru complexes
Ito, Jun-Ichi,Fujii, Kohei,Nishiyama, Hisao
supporting information, p. 601 - 605 (2013/03/13)
NCN-pincer Ru-complexes containing bis(oxazolinyl)phenyl ligands serve as suitable catalysts in the direct conjugate additions of α,β- unsaturated carbonyl compounds, including ketones, esters, and amides, as well as vinylphosphonates, giving various β-alkynyl carbonyl and phosphonate compounds. A bis(oxazolinyl)phenyl (phebox)-Ru complex also catalyzes the asymmetric conjugate addition of an alkyne with a β-substituted, α,β-unsaturated ketone to produce a chiral β-alkynyl ketone. Copyright
