62268-16-0

Basic information

• Product Name: 1,2-Benzenedicarboxylic acid, 3,4,6-trichloro-
• CAS NO: 62268-16-0
• Molecular Formula: C8H3Cl3O4
• Molecular Weight: 269.468
• Mol File: 62268-16-0.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1,2-Benzenedicarboxylic acid, 3,4,6-trichloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-Benzenedicarboxylic acid, 3,4,6-trichloro-(62268-16-0)
• EPA Substance Registry System: 1,2-Benzenedicarboxylic acid, 3,4,6-trichloro-(62268-16-0)

Safety Data

• Hazardous Substances Data: 62268-16-0(Hazardous Substances Data)

Usage

Appearance

Solid, white to off-white powder

Usage

Intermediate in the production of chemicals, dyes, pigments, and pharmaceuticals

Reactivity

Highly reactive

Chemical reactions

Esterification, amidation

Derivatives

Formation of derivatives with different physical and chemical properties

Safety precautions

Harmful if inhaled, ingested, or in contact with the skin

Handling

Handle with care due to potential hazards

Upstream product

• 117-08-8 tetrachlorophthalic anhydride 
• 59317-90-7 3,4,6-trichloro-phthalic acid anhydride 
• 7732-18-5 water 
• 56962-06-2 3,4-dichloro-phthalic acid 
• 632-58-6 tetrachlorophthalic acid 

Downstream Products

• 446-17-3 2,4,5-trifluorobenzoic acid 
• 2251-54-9 3,4,6-trifluorophthalic acid 
• 16110-99-9 3,6-dichlorophthalic acid 
• 136470-65-0 AQ4N 
• 131401-54-2 1,4-Difluoro-5,8-dihydroxyanthracene-9,10-dione 
• 4466-59-5 3,6-dichlorophthalic anhydride 
• 27563-65-1 3-chlorobenzene-1,2-dicarboxylic acid 

Relevant articles and documents

Synthetic method

A process for the preparation of the compound AQ4 of formula 3: or a salt or N-oxide thereof, includes the step:

Process improvements in the synthesis of 2,4,5-trifluorobenzoic acid. selective hydrodefluorination of tetrafluorophthalimides

An improved preparation of the fluoroquinolone antibacterial intermediate 2,4,5-trifluorobenzoic acid is described. A combination of a selective hydrodefluorination and hydrolysis reaction of 3,4,5,6-tetrafluoro-N-methylphthalimide leading to 3,5,6-trifluorophthalic acid was key to the success of the process. In addition the development of a two-step, one-pot imidization/ halogen exchange from tetrachlorophthalic anhydride to 3,4,5,6-tetrafluoro-N-methylphthalimide in sulfolane solvent is detailed.

Optimization of Reaction Variables in the Selective Hydrodechlorination of Chlorinated Phthalic Anhydrides and Acids: Preparation of 3,6-Dichlorophthalic Acid and 3-Chlorophthalic Acid

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