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6-Quinolinepropanoic acid, α-amino-2-(2,6-dichlorophenyl)-, methyl ester, also known as Flumequine, is a synthetic antimicrobial agent belonging to the quinolone class of drugs. It is primarily used in veterinary medicine for the treatment of bacterial infections in animals, particularly in cattle, pigs, and poultry. Flumequine works by inhibiting bacterial DNA synthesis, thereby preventing the growth and reproduction of harmful bacteria. Its chemical structure features a quinoline ring, a propanoic acid chain, an amino group, and a 2,6-dichlorophenyl group, with a methyl ester group attached to the α-amino position. 6-Quinolinepropanoic acid, a-amino-2-(2,6-dichlorophenyl)-, methyl ester is known for its broad-spectrum activity against gram-negative and some gram-positive bacteria, making it a valuable tool in managing various bacterial diseases in livestock.

623144-31-0

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623144-31-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 623144-31-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,2,3,1,4 and 4 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 623144-31:
(8*6)+(7*2)+(6*3)+(5*1)+(4*4)+(3*4)+(2*3)+(1*1)=120
120 % 10 = 0
So 623144-31-0 is a valid CAS Registry Number.

623144-31-0Downstream Products

623144-31-0Relevant academic research and scientific papers

2,6-Quinolinyl derivatives as potent VLA-4 antagonists

Lassoie, Marie-Agnes,Broeders, Fabienne,Collart, Philippe,Defrere, Laurent,de Laveleye-Defais, Francoise,Demaude, Thierry,Gassama, Abdoulaye,Guillaumet, Gerald,Hayez, Jean-Claude,Kiss, Laszlo,Knerr, Laurent,Nicolas, Jean-Marie,Norsikian, Stephanie,Quere, Luc,Routier, Sylvain,Verbois, Valerie,Provins, Laurent

, p. 142 - 146 (2007/10/03)

A new series of 2,6-quinolinyl derivatives was prepared leading to potent low nanomolar VLA-4/VCAM-1 antagonists.

2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS

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Page/Page column 44, (2010/02/07)

The present invention concerns 2,6-quinolinyl and 2,6-naphthyl derivatives of formula (I), processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals for the treatment of VLA-4 dependent inflammatory diseases such as for example asthma, allergic rhinitis, sinusitis, conjunctivitis, food allergy, psoriasis, urticaria, pruritus, eczema, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis and atherosclerosis. Formula (I): wherein X is N or CH.

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