62321-92-0

Basic information

• Product Name: 2-CYANO-3-(DIMETHYLAMINO)-2-BUTENAMIDE
• Synonyms: 2-CYANO-3-(DIMETHYLAMINO)-2-BUTENAMIDE
• CAS NO: 62321-92-0
• Molecular Formula: C₇H₁₁N₃O
• Molecular Weight: 153.18
• Mol File: 62321-92-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 194-196°C
• Boiling Point: 435.3°C at 760 mmHg
• Flash Point: 217°C
• Appearance: /
• Density: 1.104g/cm³
• Vapor Pressure: 8.88E-08mmHg at 25°C
• Refractive Index: 1.508
• CAS DataBase Reference: 2-CYANO-3-(DIMETHYLAMINO)-2-BUTENAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CYANO-3-(DIMETHYLAMINO)-2-BUTENAMIDE(62321-92-0)
• EPA Substance Registry System: 2-CYANO-3-(DIMETHYLAMINO)-2-BUTENAMIDE(62321-92-0)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 62321-92-0(Hazardous Substances Data)

Usage

General Description

2-Cyano-3-(dimethylamino)-2-butenamide is a chemical compound with the molecular formula C7H11N3O. It is a yellow liquid at room temperature and is classified as an organic compound. This chemical is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is known to have potential applications in medicinal chemistry due to its ability to act as a ligand or building block for the development of new drugs. Additionally, it is also used in research and development activities as a reagent in organic synthesis. Overall, 2-cyano-3-(dimethylamino)-2-butenamide has significant importance in the fields of pharmaceuticals and chemistry.

InChI:InChI=1/C7H11N3O/c1-5(10(2)3)6(4-8)7(9)11/h1-3H3,(H2,9,11)/b6-5+

Upstream product

• 18871-66-4 N,N-dimethylacetamide dimethyl acetal 
• 107-91-5 cyanoacetic acid amide 

Downstream Products

• 91255-14-0 α-Cyano-β-N-phenylaminocrotonamide 
• 62321-91-9 C₈H₉N₃O 
• 98694-78-1 C₉H₁₁N₃O 
• 376621-89-5 2-cyano-3-(3-fluoroanilino)crotonamide 
• 1292297-38-1 4-(3-fluoroanilino)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 1292297-39-2 4-(3,4-difluoroanilino)-2-oxo-1,2-dihydropyridine-3-carbonitrile 
• 1292297-43-8 2-chloro-4-(3-fluoroanilino)pyridine-3-carbonitrile 
• 1292297-45-0 2-chloro-4-(3,4-difluoroanilino)pyridine-3-carbonitrile 
• 1292297-48-3 methyl 3-amino-4-(3-fluoroanilino)thieno[2,3-b]pyridine-2-carboxylate 
• 1292297-49-4 methyl 3-amino-4-(3,4-difluoroanilino)thieno[2,3-b]pyridine-2-carboxylate 
• 1292297-53-0 methyl 3-[1-(dimethylamino)ethylidene]amino-4-(3-fluoroanilino)thieno[2,3-b]pyridine-2-carboxylate 
• 1292297-57-4 ethyl 3-[1-(dimethylamino)ethylidene]amino-4-(3-fluoroanilino)thieno[2,3-b]pyridine-2-carboxylate 
• 1292297-54-1 methyl 3-[1-(dimethylamino)ethylidene]amino-4-(3,4-difluoroanilino)thieno[2,3-b]pyridine-2-carboxylate 
• 1292297-58-5 ethyl 3-[1-(dimethylamino)ethylidene]amino-4-(3,4-difluoroanilino)thieno[2,3-b]pyridine-2-carboxylate 

Relevant articles and documents

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FUSED TRICYCLIC MGLUR1 ANTAGONISTS AS THERAPEUTIC AGENTS

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J3, X, Z, and R1-R4 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, part

mGluR1 antagonists as therapeutic agents

In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J4, X, and R1—R5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease.