62323-44-8

Basic information

• Product Name: 2-Bromo-5-ethylthiophene
• Synonyms: 2-Bromo-5-ethylthiophene;5-Bromo-2-ethylthiophene
• CAS NO: 62323-44-8
• Molecular Formula: C₆H₇BrS
• Molecular Weight: 191.09
• Mol File: 62323-44-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 78.5 °C(Press: 11 Torr)
• Appearance: /
• Density: 1.493
• CAS DataBase Reference: 2-Bromo-5-ethylthiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-5-ethylthiophene(62323-44-8)
• EPA Substance Registry System: 2-Bromo-5-ethylthiophene(62323-44-8)

Safety Data

• Hazardous Substances Data: 62323-44-8(Hazardous Substances Data)

Usage

General Description

2-Bromo-5-ethylthiophene is a chemical compound with the molecular formula C6H7BrS. It is an organobromine compound with a five-membered thiophene ring and an ethyl group attached to it. 2-Bromo-5-ethylthiophene is commonly used in organic synthesis and pharmaceutical research due to its reactivity and potential biological activities. It is known for its role in the construction of various organic molecules and as a building block in the development of new pharmaceutical drugs. Additionally, 2-Bromo-5-ethylthiophene is also used in the manufacturing of agrochemicals and advanced materials.

Upstream product

• 872-55-9 2-ethylthiophene 

Downstream Products

• 1057670-00-4 2-ethyl-5-ethynylthiophene 
• 83663-40-5 4-Bromo-2-ethylthiophene 
• 64964-17-6 5-Ethyl-2-thiophencarbonsaeurechlorid 
• 23229-72-3 5-ethyl-2-thiophenecarboxylic acid 
• 18761-46-1 1-(5-ethyl-thiophen-2-yl)-ethanone 

Relevant articles and documents

Synthesis of monochlorosilyl derivatives of dialkyloligothiophenes for self-assembling monolayer field-effect transistors

Unsymmetrical dimethylchlorosilyl-substituted α, α′- dialkylquater-, quinque-, and sexithiophenes were designed and successfully synthesized by a combination of Kumada and Suzuki cross-coupling reactions followed by hydrosilylation. Optimization possibilities of the hydrosilylation of low-soluble linear oligothiophenes by dimethylchlorosilane as well as the nonreactive byproducts formed are described. The molecular structures of the obtained dimethylchlorosilyl-functionalized oligothiophenes were proven by NMR and DCI MS techniques. These compounds were found to be stable and reactive enough, even in the presence of the nonreactive byproducts, to form semiconducting monolayers on dielectric hydroxylated SiO2 surfaces by self-assembly from solution. The semiconducting properties of these oligothiophene SAMs were as good as those of bulk oligothiophenes. This allowed the production of stable, even under ambient conditions, SAMFETs with a mobility of up to 0.04 cm2/(V s) and an on/off ratio up to 1 × 10 8.

HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF

Provided herein are thiophene compounds, methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are useful for the treatment, prevention, and/or management of various neurological disorders, including but not limited to, psychosis and schizophrenia.

Nematic 2,5-disubstituted thiophenes

A large number of new liquid crystals incorporating the 2,5-disubstituted thiophene ring have been prepared and their mesomorphic behaviour studied in order to systematically investigate the correlation between the molecular structure and mesomorphism of thiophene derivatives with different shapes, polarisability and polarity. As a consequence of these investigations we have prepared a new class of liquid crystals incorporating a 2,5-disubstituted thiophene ring and a conjugated trans-carbon-carbon double bond in the terminal chain. These novel thiophene derivatives are the first liquid crystals incorporating a 2,5-disubstituted thiophene ring to exhibit a nematic phase at room temperature. This enables the flexoelectric coefficients of a bent-shaped molecule to be measured directly and at room temperature for the first time to the authors' knowledge. Many of these new thiophenes exhibit a high birefringence and a high nematic clearing point and are of potential use as components of nematic mixtures in LCDs.