6237-24-7

Upstream product

• 1744-91-8 9-chloro-3-nitroacridine 
• 109-55-7 1-amino-3-(dimethylamino)propane 
• 32841-11-5 6-Nitro-9-phenoxyacridin 
• 27693-70-5 N-(3-nitrophenyl)anthranilic acid 
• 107-10-8 propylamine 
• 124-40-3 dimethyl amine 
• 88-67-5 2-Iodobenzoic acid 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 56739-54-9 N-(3-nitrophenyl)anthranilic acid methyl ester 

Downstream Products

• 1744-92-9 3-nitro-9,10-dihydroacridin-9-one 

Relevant academic research and scientific papers

NOVEL NUCLEIC ACID MODIFIERS

The present inventions generally relate to site-specific delivery of nucleic acid modifiers and includes novel DNA-binding proteins and effectors that can be rapidly programmed to make site-specific DNA modifications. The present inventions also provide a synthetic all-in-one genome editor (SAGE) systems comprising designer DNA sequence readers and a set of small molecules that induce double-strand breaks, enhance cellular permeability, inhibit NHEJ and activate HDR, as well as methods of using and delivering such systems.

REACTIONS AT C-9 OF ACRIDINE DERIVATIVES. PART XXVIII. KINETICS OF 1-, 2-, 3- AND 4-NITRO-9-AMINOACRIDINE SYNTHESES. SUBSTITUENT EFFECT OF THE NO2 GROUP DURING AMINOLYSIS

Spectrophotometric studies on dimethylaminopropylamine (DMAPA) reactions with 1-, 2-, 3- and 4-nitro-9-chloro(phenoxy)acridines were carried out in DMSO and in xylene.Reactions in DMSO were of the second order, with nitro isomers reacting in the sequence of 2>4>1ca.3; reactions in xylene were of the third order, with nitro isomers reacting in the sequence of 2>1>4>3; α-pyridone and triethylamine produced no catalytic effect.These data might suggest strong "para" type nitro activation for the 2-nitro isomer and significant steric interactions by nitro group to 1-nitro isomer aminolysis.