1744-92-9

Basic information

• Product Name: 3-nitroacridin-9(10H)-one
• Synonyms: 9(10H)-Acridinone, 3-nitro-
• CAS NO: 1744-92-9
• Molecular Formula: C₁₃H₈N₂O₃
• Molecular Weight: 240.2142
• Mol File: 1744-92-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 439.3°C at 760 mmHg
• Flash Point: 219.5°C
• Density: 1.409g/cm³
• Vapor Pressure: 6.46E-08mmHg at 25°C
• Refractive Index: 1.672
• CAS DataBase Reference: 3-nitroacridin-9(10H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitroacridin-9(10H)-one(1744-92-9)
• EPA Substance Registry System: 3-nitroacridin-9(10H)-one(1744-92-9)

Safety Data

• Hazardous Substances Data: 1744-92-9(Hazardous Substances Data)

Upstream product

• 1744-91-8 9-chloro-3-nitroacridine 
• 49551-01-1 2-anilino-4-nitrobenzoic acid 
• 528-75-6 2,4-dinitrobenzaldehyde 
• 71-43-2 benzene 
• 6237-24-7 N,N-dimethyl-N'-(3-nitro-9-acridinyl)-1,3-propanediamine 
• 27693-70-5 N-(3-nitrophenyl)anthranilic acid 
• 99-60-5 2-chloro-4-nitrobenzoic acid 
• 62-53-3 aniline 
• 99-09-2 3-nitro-aniline 
• 118-91-2 ortho-chlorobenzoic acid 
• 56739-54-9 N-(3-nitrophenyl)anthranilic acid methyl ester 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 88-67-5 2-Iodobenzoic acid 
• 99-55-8 2-methyl-5-nitroaniline 

Downstream Products

• 110798-72-6 4-(2-bromo-6-nitro-acridin-9-yl)-N,N-dimethyl-aniline 
• 23043-50-7 N-(acridin-3-yl)acetamide 
• 52156-62-4 2,6-diamino-9(10H)-acridone 
• 129821-08-5 3-ATA 
• 776299-28-6 3-(p-acetylaminobenzenesulphonylamino)-acridone 
• 676456-14-7 3-(p-aminobenzenesulphonylamino)acridone 
• 50433-64-2 3-amino-10H-acridin-9-one 
• 75586-71-9 9,10-dihydro-acridin-3-ylamine 
• 581-29-3 acridin-3-ylamine 

Relevant articles and documents

NOVEL NUCLEIC ACID MODIFIERS

The present inventions generally relate to site-specific delivery of nucleic acid modifiers and includes novel DNA-binding proteins and effectors that can be rapidly programmed to make site-specific DNA modifications. The present inventions also provide a synthetic all-in-one genome editor (SAGE) systems comprising designer DNA sequence readers and a set of small molecules that induce double-strand breaks, enhance cellular permeability, inhibit NHEJ and activate HDR, as well as methods of using and delivering such systems.

Inhibition of Cryptosporidium parvum in vitro by 9-(alkylthio)acridine derivatives

The synthesis of several acridinic thioethers is described. Compounds prepared were tested in vitro as potential drugs against the opportunistic infection known as cryptosporidiosis. With a view to predict activity, the quantitative structure-activity relationships were investigated. Correlations between experimental data and either log P or pKa are discussed.

Tricyclic heterocyclic derivatives

The invention relates to tricyclic heterocyclic derivatives, or pharmaceutically-acceptable salts or in vivohydrolysable esters thereof, which possess anti-cancer activity. The invention also relates to processes for the manufacture of said tricyclic hete