62378-62-5Relevant articles and documents
Biomimetic iterative method for polyketide synthesis
Akagawa, Kengo,Kudo, Kazuaki
supporting information, p. 8645 - 8648 (2017/08/10)
An iterative method for synthesizing polyketides was demonstrated, in which the chain elongation of a carboxylic acid was performed by decarboxylative dehydration condensation with a malonic acid half thioester. After transforming the resulting β-ketothioester into an appropriate form, the carboxylic acid functionality was regenerated for the next elongation step.