623926-93-2

Upstream product

• 623926-36-3 (Z,Z,Z)-(6S,7S,8S,13R,14S,15S,16S)-15-(tert-butyldimethylsilanyloxy)-7,13-bis(4-methoxybenzyloxy)-6,8,14,16-tetramethyleicosa-4,9,17,19-tetraen-1-yl tetrahydropyran-2-yl ether 
• 623926-40-9 carbamic acid (Z,Z)-(1S,2S,3R,8S,9S,10S)-3,9-bis(4-methoxybenzyloxy)-2,8,10-trimethyl-1-[(Z)-(S)-1-methylpenta-2,4-dienyl]-15-(tetrahydropyran-2-yloxy)pentadeca-6,11-dienyl ester 
• 623926-39-6 (Z,Z,Z)-(5S,6S,7S,8R,13S,14S,15S)-8,14-bis(4-methoxybenzyloxy)-5,7,13,15-tetramethyl-20-(tetrahydropyran-2-yloxy)eicosa-1,3,11,16-tetraen-6-ol 
• 623926-37-4 2-[(Z)-(6S,7S,8R)-9-Iodo-7-(4-methoxy-benzyloxy)-6,8-dimethyl-non-4-enyloxy]-tetrahydro-pyran 
• 623926-25-0 tert-Butyl-[(2S,3R,4R)-5-iodo-3-(4-methoxy-benzyloxy)-2,4-dimethyl-pentyloxy]-dimethyl-silane 
• 623926-27-2 (3S,4S,5S)-4,6-Bis-(tert-butyl-dimethyl-silanyloxy)-3,5-dimethyl-hex-1-ene 
• 623926-28-3 (2S,3S,4S)-3-(tert-butyldimethylsilanyloxy)-2,4-dimethylhex-5-en-1-ol 
• 496035-39-3 (+)-(2S,3S,4S)-5-(tert-butyldimethylsilanyloxy)-3-(4-methoxybenzyloxy)-2,4-dimethylpentan-1-ol 
• 479673-25-1 (1R,2R,3S,4S,5Z)-1-{3-(tert-butyldimethylsilanyloxy)-1-[3-(tert-butyldimethylsilanyloxy)propyl]-2,4-dimethylocta-5,7-dienyloxymethyl}-4-methoxybenzene 
• 565229-70-1 (2R,3S,4R,5R)-3,8-bis(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2,4-dimethyloctanal 
• 479673-43-3 (Z)-(4R,5S,6S,7S)-6-(tert-butyldimethylsilanyloxy)-4-(4-methoxybenzyloxy)-5,7-dimethylundeca-8,10-dien-1-ol 
• 444682-16-0 (Z)-(2S,3S,4S)-3-(4-methoxybenzyloxy)-2,4-dimethyl-9-(tetrahydropyran-2-yloxy)non-5-en-1-yl tert-butyldimethylsilyl ether 
• 261968-20-1 (-)-(2R,3R,4S)-5-(tert-butyldimethylsilanyloxy)-3-(4-methoxybenzyloxy)-2,4-dimethylpentanal 
• 184291-95-0 (2S,3S,4S)-1-(tert-butyldimethylsilanyloxy)-3-(4-methoxybenzyloxy)-2,4-dimethyl hex-5-ene 

Relevant academic research and scientific papers

Synthesis and biological assessment of simplified analogues of the potent microtubule stabilizer (+)-discodermolide

An efficient, convergent and stereocontrolled synthesis of simplified analogues of the potent antimitotic agent (+)-discodermolide has been achieved and several small libraries have been prepared. In all the libraries, the discodermolide methyl groups at