62437-21-2Relevant academic research and scientific papers
Synthesis and biological evaluation of analogues of the anti-tumor alkaloid naamidine A
Aberle, Nicholas,Catimel, Jenny,Nice, Edouard C.,Watson, Keith G.
, p. 3741 - 3744 (2008/02/12)
A small series of derivatives of the alkaloid naamidine A was synthesized and tested in vitro for their ability to inhibit mitogenesis in BaF/ERX cells. Replacement of the imidazole core with a thiazole was found to have only a minor effect on potency, and the 4-methoxybenzyl substituent of the natural product was shown to be unnecessary for activity.
