6245-50-7Relevant academic research and scientific papers
Self-assembly of bis-[1]rotaxanes based on diverse thiourea-bridged mono-functionalized dipillar[5]arenes
Yang, Lu,Nie, Cui-Yun,Han, Ying,Sun, Jing,Yan, Chao-Guo
, p. 89 - 97 (2021/09/06)
The condensation reaction of mono-amido-functionalized pillar[5]arenes with tere- and iso-phthaloyl diisothiocyanates in acetone under ultrasonic irradiation afforded tere- and iso-phthaloylthiourea-bridged dipillar[5]arenes. The similar reaction of mono-
BIVALENT LECA INHIBITORS TARGETING BIOFILM FORMATION OF PSEUDOMONAS AERUGINOSA
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, (2021/05/15)
The present invention relates to divalent compounds binding to LecA. The compounds are useful to block biofilm formation of Pseudomonas aeruginosa. The invention further relates to pharmaceutical compositions comprising these compounds and to therapeutic methods and uses of these compounds, in particular to therapeutic methods and uses for the treatment of Pseudomonas aeruginosa infections in a subject. The invention also relates to imaging of infections, such as biofilms produced by Pseudomonas aeruginosa, by using these divalent compounds.
Identification and validation of small molecule modulators of the NusB-NusE interaction
Cossar, Peter J.,Ma, Cong,Gordon, Christopher P.,Ambrus, Joseph I.,Lewis, Peter J.,McCluskey, Adam
, p. 162 - 167 (2016/12/27)
Formation of highly possessive antitermination complexes is crucial for the efficient transcription of stable RNA in all bacteria. A key step in the formation of these complexes is the protein-protein interaction (PPI) between N-utilisation substances (Nu
Thermal and mechanical properties of azomethine functionalized cyanate ester/epoxy blends
Sakthidharan,Sundararajan,Sarojadevi
, p. 19666 - 19674 (2015/05/12)
A series of azomethine functionalized diols were synthesized by the condensation reaction of aromatic diamines with 4-hydroxy benzaldehyde. Aromatic diamines with different alkyl chain lengths have been used to prepare the bisphenols. These bisphenols wer
N-(2-METHYL-2-NITROPROPYL) AND N-NITROSO DERIVATIVES OF SOME DIAMINES
Kafka, Stanislav,Klasek, Antonin,Sedmera, Petr
, p. 1541 - 1550 (2007/10/02)
Preparation of ten new derivatives of 1,6-hexanediamine and 1,4-bis(4-aminophenoxy)butane with different combination of N-nitroso and/or N-(2-methyl-2-nitropropyl) groups is presented.The title compounds are potential improvers of vulcanized rubber dynamic properties.
Biological properties of amidinium sulfinic and sulfonic acid derivatives: inhibition of glycolytic enzymes of Trypanosoma brucei and protective effect on cell growth
Willson, M,Perie, JJ,Malecaze, F,Opperdoes, F,Callens, M
, p. 799 - 808 (2007/10/02)
The activity of the title compounds has been investigated on two biological targets: cultures of trypanosome and glycolytic enzymes inhibition of the parasite, and on retinal epithelium cells.In both cases, these compounds exhibit a significant activity,
BIS-IMIDAZOLINOAMINO DERIVATIVES AS ANTIALLERGY COMPOUNDS
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, (2008/06/13)
This invention relates to chemical compounds which possess valuable therapeutic activity particularly as lipoxygenase and phospholipase C inhibitors and as platelet-activating factor receptor antagonists. The compounds posses anti-inflammatory anti-asthma
Novel Bis as Antitrypanosomal Agents
Turner, William R.,Werbel, Leslie M.
, p. 1728 - 1740 (2007/10/02)
A series of novel 1,1'-(4,1-phenylene)bis was prepared and evaluated for activity against Trypanosoma rhodesiense in mice.The importance of the bis structure and the nature of the spacer between the two phenyl rings for optimal activity have been revealed.The potent parenteral activity of several analogues within this series as well as preliminary indication of oral activity lends encouragement to further development of this structural class.
MESOGENIC POLYMERS. 6. TWO SERIES OF ISOMERIC POLYAZOMETHINES.
Griffin,Britt,Hung,Steele
, p. 305 - 314 (2007/10/02)
Two homologoous series of alternating rigid-flexible, main chain liquid crystalline polyimines are reported; one based on terephthaldehyde the other based on p-phenylenediamine. It was found through examination of optical microscopic, x-ray diffraction an
Poly(6-oxy-2,2,4-trialkyl-1,2-dihydroquinoline)alkylene compounds as antidegradants for rubber
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, (2008/06/13)
Vulcanizable or vulcanized diene elastomers containing stabilizing amounts of certain poly(6-oxy-2,2,4-trialkyl-1,2-dihydroquinoline)alkylene antidegradants show resistance to ozone attack. The antidegradants themselves are novel compounds.
